Classification of Mouse Transcription Factors - Draft September 22, 2014 -

This classification is the working version that comprises only murine transcription factors (TFs) that have human orthologs, with few exceptions. In particular many mouse-specific TFs are still missing in Class 2.3 (C2H2 zinc finger factors). As for the classification of the human TFs, it may be subject to occasional changes, suggested for discussion. Symbols / links: : TRANSFAC® class descriptions; : new class descriptions; : additional information about the class and its members (see below); : Link to reviewed mouse entries UniProt; : Link to unreviewed mouse entries UniProt; : Link to reviewed human UniProt entries; /: Link to reviewed/unreviewed rat UniProt entries, resp. "Txxxxx": TRANSFAC accession numbers, mostly linked to BIOBASE Knowledge Library (BKL); "T" only provides a link to a BKL entry that has no TRANSFAC accession yet. : Link to PDB; preferably to a complex of the corresponding DNA-binding domain (DBD) with DNA, provisionally the DBD alone, referring to the human or a mammalian ortholog; for a few excpetions, illustrative structures of fungal homologs are linked. Additional information: The question mark in the Class title line links to the class description, the sequences of the manually adjusted DNA-binding domains of this respective class and their alignments, logo plots and, whenever relevant, further information like dimerization matrices etc. DNA sequence patterns: The DNA sequences assigned to many families or subfamilies represent typical or proven individual binding sequences for (some of) the domains in the respective taxon. They should not be taken as a consensus, and they are not suitable for predicting potential TF binding sites. The logo plots after many TF genera have been derived from the profile library published by the group of J. Taipale at Karolinska Institute (Jolma et al., Cell 152, 327-339 (2013); PubMed 23332764) and were kindly provided by P. Stegmaier (geneXplain GmbH). Each of these plots is linked to an htm file with all matrices for this factor, human and mouse, that were given by Jolma et al., one of them being selected for the logo plot. The individual matrices are given a unique ID, comprising the gene symbol of the factor and an alphanumeric specification of the respective matrix, which may be either a consecutive number, or may have an additional "m" to indicate monomeric factor binding mode, "d" for dimers, or "dd" for dimers of dimers bound to the respective sequence patterns. For further explanation of the information provided with each matrix, kindly refer to the original publication. Citation: Wingender, E., Schoeps, T. and Dönitz, J.: TFClass: An expandable hierarchical classification of human transcription factors. Nucleic Acids Res. 41, D165-D170 (2013). doi: 10.1093/nar/gks1123 (Link)

1

Superclass: Basic domains

1.1

Class: Basic leucine zipper factors (bZIP)

1.1.1

Family: Jun-related factors

TGAGTCA

1.1.1.1

Subfamily: Jun factors

TGAGTCA

1.1.1.1.1

c-Jun

T00131

1.1.1.1.2

JunB

T00436

1.1.1.1.3

JunD

T00437

1.1.1.2

Subfamily: NF-E2-like factors

GCTGAGTCA

1.1.1.2.1

NF-E2 p45

T01441

1.1.1.2.2

NF-E2L1 (NRF1)

T02203

1.1.1.2.2.1

NF-E2L1, isoform 1 (Nrf1a)

T09558

1.1.1.2.2.2

NF-E2L1, isoform 2 (Nrf1b)

T28874

1.1.1.2.2.3

NF-E2L1, isoform 3 (short)

T13800

1.1.1.2.3

NF-E2L2 (NRF2)

T04938

1.1.1.2.4

NF-E2L3 (NRF3)

T05710

1.1.1.2.5

BACH1

T04793

1.1.1.2.6

BACH2

T04792

1.1.1.3

Subfamily: ATF-2-like factors

TGACGTCA

1.1.1.3.1

ATF-2

T10238

1.1.1.3.1.1

ATF-2, isoform 1

T02056

1.1.1.3.1.2

ATF-2, isoform 2

T01017

1.1.1.3.1.3

ATF-2, isoform 3

T02036

1.1.1.3.2

ATF-7

T19847

1.1.1.3.3

CREB-5 (CRE-BPa)

T18881

1.1.1.3.3.1

CREB-5, isoform 1

T18880

1.1.1.3.3.2

CREB-5, isoform 2

T18882

1.1.2

Family: Fos-related factors

(TGAGTCA)

1.1.2.1

Subfamily: Fos factors

(TGAGTCA)

1.1.2.1.1

c-Fos

T00122

1.1.2.1.2

FosB

T10574

1.1.2.1.3

Fra-1

T00292

1.1.2.1.4

Fra-2

T02199

1.1.2.1.4.1

Fra-2, isoform 1

T08535

1.1.2.1.4.2

Fra-2, isoform 2

T26121

1.1.2.2

Subfamily: ATF-3-like factors

TGACGTCA

1.1.2.2.1

ATF-3

T08977

1.1.2.2.1.1

ATF-3, isoform 1

T04850

1.1.2.2.1.2

ATF-3, isoform 2 (ATF-3b)

T08976

1.1.2.2.2

JDP-2

T19034

1.1.3

Family: Maf-related factors

TGCTGACTCAGCA

1.1.3.1

Subfamily: Large Maf factors

TGCTGACTCAGCA

1.1.3.1.1

c-Maf

T01432

1.1.3.1.1.1

c-Maf, isoform 1

T09212

1.1.3.1.1.2

c-Maf, isoform 2

T26181

1.1.3.1.1.3

c-Maf, isoform 3

T26182

1.1.3.1.2

MafA

T08226

1.1.3.1.3

MafB

T01439

1.1.3.1.4

Nrl

T01438

1.1.3.2

Subfamily: Small Maf factors

TGCTGACTCAGCA

1.1.3.2.1

MafF

T05751

1.1.3.2.2

MafG

T05750

1.1.3.2.3

MafK

T01435

1.1.4

Family: B-ATF-related factors

TGAGTCA

1.1.4.0.1

B-ATF

T19854

1.1.4.0.2

B-ATF-2

T

1.1.4.0.2.1

B-ATF-2, isoform 1

T

1.1.4.0.2.2

B-ATF-2, isoform 2

T

1.1.4.0.3

B-ATF-3

T18807

1.1.5

Family: XBP-1-related factors

GGATGACGTGTACA

1.1.5.0.1

XBP-1

T08152

1.1.5.0.1.1

XBP-1U

T19362

1.1.5.0.1.2

XBP-1S

T11222

1.1.6

Family: ATF-4-related factors

TGACGTCA

1.1.6.0.1

ATF-4

T08444

1.1.6.0.2

ATF-5

T16632

1.1.7

Family: CREB-related factors

TGACGTCA

1.1.7.1

Subfamily: CREB-like factors

TGACGTCA

1.1.7.1.1

CREB (CREB-1)

T02280

1.1.7.1.1.1

CREB, isoform 1 (CREBα)

T00989

1.1.7.1.1.2

CREB, isoform 2 (CREBΔ)

T01311

1.1.7.1.1.3

CREB, isoform 3 (CREBβ)

T02361

1.1.7.1.1.4

CREB, isoform 4 (CREBω)

T01312

1.1.7.1.2

ATF-1

T01304

1.1.7.1.3

CREM

T10306

1.1.7.1.3.1

CREM-τ, isoform 1 (CREM-BCEFGγHIβ)

T01320

1.1.7.1.3.2

CREM-α, isoform 2

T01314

1.1.7.1.3.3

CREM-β, isoform 3

T01315

1.1.7.1.3.4

CREM-γ, isoform 4

T01316

1.1.7.1.3.5

CREM-ταγ, isoform 5

T26061

1.1.7.1.3.6

CREM-τ2α, isoform 6

T26062

1.1.7.1.3.7

CREM-τ1α, isoform 7

T26063

1.1.7.1.3.8

CREM-τ1αγ, isoform 8

T26064

1.1.7.1.3.9

CREM-τ1γ, isoform 9

T26065

1.1.7.1.3.10

CREM-αγ, isoform 10

T26376

1.1.7.2

Subfamily: CREB-3-like factors

TGACGTCA

1.1.7.2.1

CREB-3 (Luman, LZIP)

T18876

F

1.1.7.2.1.1

CREB-3, isoform 1 (LZIP-1)

T18875

1.1.7.2.1.2

LZIP, isoform 2 (LZIP-2)

T18874

1.1.7.2.2

CREB-3L1 (OASIS)

T18855

1.1.7.2.2.1

CREB-3L1, isoform 1

T18854

1.1.7.2.2.2

CREB-3L1, isoform 2

T18853

1.1.7.2.3

CREB-3L2

T15600

1.1.7.2.4

CREB-3L3 (CREB-H)

T18861

1.1.7.2.5

CREB-3L4 (AIBZIP)

T18868

1.1.7.2.5.1

CREB-3L4, isoform 1 (Tisp40β)

T18866

1.1.7.2.5.2

CREB-3L4, isoform 2 (Tisp40α)

T18867

1.1.7.3

Subfamily: ATF-6 factors

TGACGTGG

1.1.7.3.1

ATF-6α

T26785

1.1.7.3.2

ATF-6β

T18795

1.1.7.4

Subfamily: CREBZF-like factors

TGACGTCA

1.1.7.4.1

CREBZF (Zhangfei, ZF)

T

1.1.7.5

Subfamily: CREBL2-like factors

TGACGTCA

1.1.7.5.1

CREBL2

T19897

1.1.8

Family: C/EBP-related

ATTGCGCAAT

1.1.8.1

Subfamily: C/EBP

ATTGCGCAAT

1.1.8.1.1

C/EBPα

T08464

1.1.8.1.2

C/EBPβ (NF-IL6-1)

T09409

1.1.8.1.2.1

C/EBPβ, isoform 1 (C/EBPβ-FL)

T00017

1.1.8.1.2.2

C/EBPβ, isoform 2 (C/EBPβ-LAP)

1.1.8.1.2.3

C/EBPβ, isoform 3 (C/EBPβ-LIP)

T02360

1.1.8.1.3

C/EBPγ

T00216

1.1.8.1.4

C/EBPδ

T01114

1.1.8.1.5

C/EBPε

T16653

1.1.8.1.6

DDIT3 (CHOP-10)

T00127

1.1.8.2

Subfamily: PAR factors

TTATGCAA

1.1.8.2.1

DBP

T05865

1.1.8.2.2

HLF

T19989

1.1.8.2.3

TEF

T10579

1.1.8.2.3.1

TEF-α

T10575

1.1.8.2.3.2

TEF-β

T10576

1.1.8.2.3.3

TEF, isoform 2

T10577

1.1.8.2.4

NF-IL3 (E4BP4)

T16464

1.1.0

Family: ZIP only

1.1.0.1

Subfamily: TSC22

1.1.0.1.1

TSC22D1 (TSC-22, Cerebral protein 2)

T27854

1.1.0.1.1.1

TSC22D1, isoform 1

T27936

1.1.0.1.1.2

TSC22D1, isoform 2

T27360

1.1.0.1.1.3

TSC22D1, isoform 3

T27937

1.1.0.1.2

TSC22D2 (TILZ4)

T

1.1.0.1.3

TSC22D3 (DSIPI, GILZ)

T22155

1.1.0.1.3.1

TSC22D3, isoform 1 (Tilz3b)

T25737

1.1.0.1.3.2

TSC22D3, isoform 2 (Tilz3a)

T25738

1.1.0.1.3.3

TSC22D3, isoform 3 (Tilz3c)

T25739

1.1.0.1.4

TSC22D4 (TILZ2)

T

1.1.0.2

Subfamily: UTF

1.1.0.2.1

UTF1

T09523

1.1.0.2.1.1

UTF1, isoform 1

T08886

1.1.0.2.1.2

UTF1, isoform 2

T26349

1.2

Class: Basic helix-loop-helix factors (bHLH)

1.2.1

Family: E2A-related factors

CAGGTG

1.2.1.0.1

E2A (TCF-3, ITF-1)

T10541

1.2.1.0.1.1

E12 (PAN-2)

T01786

1.2.1.0.1.2

E47 (PAN-1)

T01788

1.2.1.0.2

SEF2 (E2-2, TCF-4, ITF-2, MITF)

T19028

1.2.1.0.2.1

SEF2, isoform 1 (MITF-2A)

T19025

1.2.1.0.2.2

SEF2, isoform 2 (MITF-2B)

T19027

1.2.1.0.2.3

SEF2, isoform 3 (MITF-2BΔ)

T19026

1.2.1.0.3

HTF-4 (TCF-12, HEB)

T09513

1.2.1.0.3.1

HTF-4a, isoform 1 (ME1A; α)

T01496

1.2.1.0.3.2

HTF-4b, isoform 2 (ME1B; γ)

T01497

1.2.2

Family: MyoD / ASC-related factors

CAGGTG

1.2.2.1

Subfamily: Myogenic transcription factors

1.2.2.1.1

MyoD (Myod1)

T00506

1.2.2.1.2

Myogenin (Myog, Myf-4)

T00528

1.2.2.1.3

Myf-5

T01534

1.2.2.1.4

Myf-6 (MRF4)

T16555

1.2.2.2

Subfamily: Achaete-Scute-like factors

1.2.2.2.1

ASH-1 (ASCL1)

T01619

1.2.2.2.2

ASH-2 (ASCL2)

T16775

1.2.2.2.3

ASH-3 (ASCL3)

T19843

1.2.2.2.4

ASH-4 (ASCL4)

T

1.2.2.2.5

ASH-5 (ASCL5)

T

1.2.3

Family: Tal-related factors

CAGCTG

1.2.3.1

Subfamily: Tal / HEN-like factors

CAGCTG

1.2.3.1.1

Tal-1 (SCL, TCL-5)

T16151

1.2.3.1.2

Tal-2

T01631

1.2.3.1.3

Lyl-1

T

1.2.3.1.4

HEN1 (NSCL-1, NHLH1)

T01655

1.2.3.1.5

HEN2 (NSCL-2, NHLH2)

T01657

1.2.3.2

Subfamily: Twist-like factors

CGTCTG

1.2.3.2.1

Twist-1 (H-Twist, M-Twist)

T01635

1.2.3.2.2

Twist-2 (Dermo-1)

T02404

1.2.3.2.3

HAND-1 (eHAND, Th1)

T01569

1.2.3.2.4

HAND-2 (dHAND)

T04370

1.2.3.2.5

bHLH-EC2 (TCF-15)

T01613

1.2.3.2.6

Scx

T19232

1.2.3.2.7

PTF-1a

T01227

1.2.3.2.8

FIGα

T15614

1.2.3.3

Subfamily: Mesp-like factors

1.2.3.3.1

Mesp-1

T20013

1.2.3.3.2

Mesp-2

T06095

1.2.3.3.3

TCF-23

T

1.2.3.3.4

ABF-1 (Musculin, MyoR, MSC)

T05193

1.2.3.3.5

Pod-1 (TCF-21)

T19300

1.2.3.3.6

Mesogenin-1 (MSGN1)

T20026

1.2.3.4

Subfamily: Neurogenin / Atonal-like factors

CAGCTG

1.2.3.4.1

NeuroD1

T01626

1.2.3.4.2

NeuroD2

T17539

1.2.3.4.3

NeuroD4 (ATH-3)

T20046

1.2.3.4.4

NeuroD6 (ATH-2)

T01629

1.2.3.4.5

NGN-1 (NeuroD3)

T08093

1.2.3.4.6

NGN-2 (Atoh4, NeuroG2)

T08094

1.2.3.4.7

NGN-3 (Atoh5, NeuroG3)

T06058

1.2.3.4.8

ATH-1 (ATOH-1)

T01668

1.2.3.4.9

ATH-5 (ATOH-7)

T18802

1.2.3.4.10

ATH-6 (ATOH-8)

T19852

1.2.3.4.11

bHLHe22 (Beta3)

T

1.2.3.4.12

bHLHe23

T

1.2.3.4.13

OLIGO1

T05853

1.2.3.4.14

OLIGO2

T05852

1.2.3.4.15

OLIGO3

T20054

1.2.3.4.16

MIST1 (bHLHa15)

T

1.2.3.4.17

Fer3L (Ferd3L)

T19925

1.2.3.5

Subfamily: bHLHa9-like factors

1.2.3.5.1

bHLHa9

T

1.2.4

Family: Hairy-related factors

CACGAG

1.2.4.1

Subfamily: Hairy-like factors

CACGAG

1.2.4.1.1

HES-1

T09896

1.2.4.1.2

HES-2

T

1.2.4.1.3

HES-3

T05081

1.2.4.1.5

HES-5

T18965

1.2.4.1.6

HES-6

T27825

1.2.4.1.7

HES-7

T19984

1.2.4.1.8

HEY-1

T05077

1.2.4.1.9

HEY-2

T05083

1.2.4.1.10

HEYL (HRT3)

T05082

1.2.4.1.11

HELT

T16559

1.2.4.1.12

DEC1 (STRA-13, bHLHb2)

T02327

1.2.4.1.13

DEC2 (bHLHb3)

T05845

1.2.5

Family: PAS domain factors

CACGC

1.2.5.1

Subfamily: Ahr-like factors

CACGC

1.2.5.1.1

AhR

T00194

1.2.5.1.2

AhRR

T18746

1.2.5.1.2.1

AhRR, isoform 1

T05429

1.2.5.1.2.2

AhRR, isoform 2

T26012

1.2.5.1.2.3

AhRR, isoform 3

T26013

1.2.5.1.3

SIM1

T20110

1.2.5.1.4

SIM2

T19235

1.2.5.1.5

HIF-1α

T04666

1.2.5.1.5.1

HIF-1α, isoform 1

T18977

1.2.5.1.5.2

HIF-1α, isoform 2

T26140

1.2.5.1.6

HIF-3α

T18986

1.2.5.1.6.1

HIF-3α, isoform 1

T18988

1.2.5.1.6.2

HIF-3α, isoform 2

T18987

1.2.5.1.7

EPAS-1

T02719

1.2.5.1.8

NPAS-1

T05876

1.2.5.1.9

NPAS-3

T05878

F

1.2.5.2

Subfamily: Arnt-like factors

CACGTG

1.2.5.2.1

Arnt (HIF-1β)

T01797

1.2.5.2.1.1

Arnt long, isoform 1

T10458

1.2.5.2.1.2

Arnt short, isoform 2

T18790

1.2.5.2.2

Arnt-2

T18787

1.2.5.2.2.1

Arnt-2, isoform 1

T18785

1.2.5.2.2.2

Arnt-2, isoform 2

T18786

1.2.5.2.3

ArntL (Bmal1)

T05869

1.2.5.2.3.1

ArntL, isoform 1 (b')

T10228

1.2.5.2.3.2

ArntL, isoform 2 (b)

T18818

1.2.5.2.3.3

ArntL, isoform 3

T18819

1.2.5.2.3.4

ArntL, isoform 4

T18820

1.2.5.2.3.5

ArntL, isoform 5 (g')

T18821

1.2.5.2.4

ArntL2 (Bmal2)

T05874

1.2.5.2.4.1

ArntL2, isoform 1 (Bmal2a)

T11140

1.2.5.2.4.2

ArntL2, isoform 2 (Bmal2b)

T26045

1.2.5.2.5

CLOCK

T05868

1.2.5.2.5.1

CLOCK, isoform Long

T10259

1.2.5.2.5.2

CLOCK, isoform Short

T18843

1.2.5.2.6

NPAS-2

T05877

1.2.5.3

Subfamily: NCoA factors

1.2.5.3.1

NCoA-1 (SRC-1)

T04639

1.2.5.3.1.1

NCoA-1, isoform 1 (SRC-1A)

T25725

1.2.5.3.1.2

NCoA-1, isoform 2 (SRC-1E)

T09181

1.2.5.3.1.3

NCoA-1, isoform 3

T26206

1.2.5.3.1.4

NCoA-1, isoform 4

T26207

1.2.5.3.2

NCoA-2

T02482

1.2.5.3.3

NCoA-3

T04638

1.2.5.4

Subfamily: NPAS-4

CACGA

1.2.5.4.1

NPAS-4

T

1.2.5.5

Subfamily: SOHLH-like factors

1.2.5.5.1

SOHLH1 (TEB2)

T20117

1.2.5.5.2

SOHLH2 (TEB1)

T19246

1.2.5.5.3

TCFL5 (Cha, E2BP-1)

T17742

F

1.2.6

Family: bHLH-ZIP factors

CACATG

1.2.6.1

Subfamily: TFE3-like factors

CACATG

1.2.6.1.1

TFE3 (TFEA)

T09192

1.2.6.1.1.1

TFE3, isoform 1

T19333

1.2.6.1.1.2

TFE3, isoform 2

T26336

1.2.6.1.1.3

TFE3, isoform 3

T26337

1.2.6.1.1.4

TFE3, isoform 4

T26338

1.2.6.1.2

TFEB

T06082

1.2.6.1.3

TFEC

T14666

1.2.6.1.4

MiTF

T01554

1.2.6.1.4.1

MiTF, isoform A

T19067

1.2.6.1.4.2

MiTF, isoform A1

T19068

1.2.6.1.4.3

MiTF, isoform A2

T19066

1.2.6.1.4.4

MiTF, isoform H

T19065

1.2.6.1.4.5

MiTF, isoform H1

T19069

1.2.6.1.4.6

MiTF, isoform H2

T19070

1.2.6.1.4.7

MiTF, isoform H3

T19071

1.2.6.1.4.8

MiTF, isoform M

T09287

1.2.6.1.4.9

MiTF, isoform M1

T19072

1.2.6.2

Subfamily: USF factors

CACGTG

1.2.6.2.1

USF-1

T00877

1.2.6.2.2

USF-2

T01555

1.2.6.2.2.1

USF-2A

T08315

1.2.6.2.2.2

USF-2B

T11000

1.2.6.3

Subfamily: SREBP factors

ATCACCCCAC

1.2.6.3.1

SREBP-1 (SREBF1)

T10488

1.2.6.3.1.1

SREBP-1A

T15263

1.2.6.3.1.2

SREBP-1A-W42

T26305

1.2.6.3.1.3

SREBP-1C

T08890

1.2.6.3.1.4

SREBP-1C-W42

T26306

1.2.6.3.2

SREBP-2 (SREBF2)

T15631

1.2.6.3.2.1

SREBP-2, isoform 1

T19272

1.2.6.3.2.2

SREBP-2, isoform 2

T26307

1.2.6.4

Subfamily: AP-4

CAGCTG

1.2.6.4.1

AP-4

T16526

1.2.6.5

Subfamily: Myc / Max factors

CACGTG

1.2.6.5.1

c-Myc

T00143

1.2.6.5.2

N-Myc

T01445

1.2.6.5.3

L-Myc-1

T02387

1.2.6.5.5

Max

T16608

1.2.6.5.6

B-Myc

T10695

1.2.6.6

Subfamily: Mondo-like factors

CACGTG

1.2.6.6.1

Mlx (Tcfl4)

T05123

1.2.6.6.1.1

Mlxα

T19092

1.2.6.6.1.2

Mlxβ

T08952

1.2.6.6.1.3

Mlxγ

T19093

1.2.6.6.2

MondoA (Mlx-IP)

T05125

1.2.6.6.2.1

Mlx-IP, isoform 1

T18651

1.2.6.6.2.2

Mlx-IP, isoform 2

T18652

1.2.6.6.3

MondoB (Mlx-IPL, WS-bHLH)

T05122

1.2.6.6.3.1

Mlx-IPL, isoform 1 (ζ)

T14593

1.2.6.6.3.2

Mlx-IPL, isoform 2 (ϑ)

T26195

1.2.6.6.3.3

Mlx-IPL, isoform 3 (ι)

T26196

1.2.6.6.3.4

Mlx-IPL, isoform 4 (κ)

T26197

1.2.6.6.3.5

Mlx-IPL, isoform 5 (η)

T26198

1.2.6.7

Subfamily: Mad-like factors

CACGTG

1.2.6.7.1

Mad1 (MXD1)

T02390

1.2.6.7.2

Mad3 (MXD3)

T02391

1.2.6.7.3

Mad4 (MXD4)

T02392

1.2.6.7.4

Mad5 (MGA) = 6.5.5.0.2

T03940

1.2.6.7.4.1

Mad5, isoform 1

T14744

1.2.6.7.4.2

Mad5, isoform 2

T26191

1.2.6.7.4.3

Mad5, isoform 3

T26192

1.2.6.7.4.4

Mad5, isoform 4

T26193

1.2.6.7.5

Mxi-1

T09074

1.2.6.7.5.1

Mxi-1, isoform 1 (long)

T09075

1.2.6.7.5.2

Mxi-1, isoform 2 (short)

T09076

1.2.6.7.6

Mnt

T03269

F

1.2.8

Family: HLH domain only

1.2.8.0.1

Id1

T00403

1.2.8.0.1.1

Id1, isoform Long

T25726

1.2.8.0.1.2

Id1, isoform Short

T09185

1.2.8.0.2

Id2

T00404

1.2.8.0.3

Id3

T00367

1.2.8.0.4

Id4

T01658

1.3

Class: Basic helix-span-helix factors (bHSH)

1.3.1

Family: AP-2

GCCTGAGGC

1.3.1.0.1

AP-2α

T10025

1.3.1.0.1.1

AP-2α, isoform 1

T00033

1.3.1.0.1.2

AP-2α, isoform 2

T02488

1.3.1.0.1.3

AP-2α, isoform 3

T02489

1.3.1.0.1.4

AP-2α, isoform 4

T02490

1.3.1.0.2

AP-2β

T02469

1.3.1.0.3

AP-2γ

T02470

1.3.1.0.4

AP-2δ

T06431

1.3.1.0.5

AP-2ε

T16752

2

Superclass: Zinc-coordinating DNA-binding domains

2.1

Class: Nuclear receptors with C4 zinc fingers

2.1.1

Family: Steroid hormone receptors (NR3)

2.1.1.1

Subfamily: GR-like receptors (NR3C)

AGAACATGATGTTCT

2.1.1.1.1

Glucocorticoid receptor (GR) (NR3C1)

T00335

2.1.1.1.1.1

GR, isoform 1 (A, 1-A)

T08555

2.1.1.1.1.2

GR, isoform 2 (B, 2-A)

T18951

2.1.1.1.1.3

GR, isoform 1-B

2.1.1.1.1.4

GR, isoform 2-B

2.1.1.1.2

Mineralocorticoid receptor (MR) (NR3C2)

T17766

2.1.1.1.3

Progesterone receptor (PR) (NR3C3)

T04680

2.1.1.1.4

Androgen receptor (AR) (NR3C4)

T00041

2.1.1.2

Subfamily: ER-like receptors (NR3A&B)

AGGTCACAGTGACCT

2.1.1.2.1

Estrogen receptor α (ERα) (ESR1, NR3A1)

T00259

2.1.1.2.2

Estrogen receptor β (ERβ) (NR3A2)

T17427

2.1.1.2.2.1

ERβ1, isoform 1

T18909

2.1.1.2.2.2

ERβ2, isoform 2

T18910

2.1.1.2.2.3

ERβ2A, isoform 3 (5A)

T18912

2.1.1.2.2.4

ERβ3, isoform 4

T26417

2.1.1.2.2.5

ERβ4, isoform 5

T26418

2.1.1.2.3

ERR1 (ERRα, ESRRA) (NR3B1)

T04849

2.1.1.2.4

ERR2 (ERRβ, ESRRB) (NR3B2)

T06175

2.1.1.2.5

ERR3 (ERRγ, ESRRG) (NR3B3)

T14585

2.1.1.2.5.1

ERR3, isoform 1

T04644

2.1.1.2.5.2

ERR3, isoform 2

T04647

2.1.2

Family: Thyroid hormone receptor-related factors (NR1)

2.1.2.1

Subfamily: Retinoic acid receptors (NR1B)

TGACCTTTGACCT

2.1.2.1.1

RAR-α (NR1B1)

T01327

2.1.2.1.1.1

RAR-α1

T01335

2.1.2.1.1.2

RAR-α2

T01336

2.1.2.1.2

RAR-β (NR1B2)

T01328

2.1.2.1.2.1

RAR-β1

T01337

2.1.2.1.2.2

RAR-β2

T01338

2.1.2.1.2.3

RAR-β3

T01339

2.1.2.1.2.4

RAR-β4

T01361

2.1.2.1.3

RAR-γ (NR1B3)

T01329

2.1.2.1.3.1

RAR-γ, isoform 1 (A)

T01340

2.1.2.1.3.2

RAR-γ, isoform 2 (B)

T26259

2.1.2.1.3.3

RAR-γ, isoform 3

T26260

2.1.2.2

Subfamily: Thyroid hormone receptors (NR1A)

TGACCTGAAATGACCT

2.1.2.2.1

T3R-α (THRA) (NR1A1)

T08894

2.1.2.2.1.1

T3R-α1

T00836

2.1.2.2.1.2

T3R-α2

T01173

2.1.2.2.1.3

T3R-α3

T17546

2.1.2.2.1.4

T3R-αΔE6

T26340

2.1.2.2.2

T3R-β (NR1A2)

T08896

2.1.2.2.2.1

T3R-β1

T04722

2.1.2.2.2.2

T3R-β2

T04723

2.1.2.3

Subfamily: Rev-ErbA (NR1D)

TGACCTAGTGACCT

2.1.2.3.1

Rev-ErbAα (NR1D1)

T06117

2.1.2.3.2

Rev-ErbAβ (NR1D2)

T04896

2.1.2.4

Subfamily: Vitamin D receptor (NR1I)

TGACCTTCGTGACCT

2.1.2.4.1

VDR (NR1I1)

T00883

2.1.2.4.2

PXR (NR1I2)

T08235

2.1.2.4.2.1

PXR, isoform 1 (PXR.1)

T04618

2.1.2.4.2.2

PXR, isoform 2 (PXR.2)

T04619

2.1.2.4.3

CAR (NR1I3)

T05687

2.1.2.4.3.1

CAR1

T08261

2.1.2.4.3.2

CAR2

T02755

2.1.2.5

Subfamily: PPAR (NR1C)

TGACCTTTGACCT

2.1.2.5.1

PPARα (NR1C1)

T00694

2.1.2.5.2

PPARβ (PPARδ) (NR1C2)

T04781

2.1.2.5.3

PPARγ (NR1C3)

T05347

2.1.2.5.3.1

PPARγ1, isoform 1

T02529

2.1.2.5.3.2

PPARγ2, isoform 2

T05332

2.1.2.6

Subfamily: ROR (NR1F)

TGACCTACTTAT

2.1.2.6.1

RORα (NR1F1)

T06119

F

2.1.2.6.1.1

RORα1

T09284

2.1.2.6.1.2

RORα2

2.1.2.6.1.3

RORα3

2.1.2.6.1.4

RORα4

T15650

2.1.2.6.2

RORβ (NR1F2)

T17581

2.1.2.6.2.1

RORβ, isoform 1

T19213

2.1.2.6.2.2

RORβ, isoform 2

T17683

2.1.2.6.3

RORγ (NR1F3)

T10351

2.1.2.6.3.1

RORγ, isoform 1

T06118

2.1.2.6.3.2

RORγ, isoform 2 (RORgT)

T10350

2.1.2.7

Subfamily: LXR (NR1H)

TGACCTCTACTGACCT

2.1.2.7.1

LXRα (NR1H3)

T04430

2.1.2.7.2

LXRβ (NR1H2)

T04467

2.1.2.7.3

FXR (NR1H4)

T02753

2.1.2.7.3.1

FXR, isoform 1

T09890

2.1.2.7.3.2

FXR, isoform 2

T09299

2.1.3

Family: RXR-related receptors (NR2)

(TGACCT)

2.1.3.1

Subfamily: Retinoid X receptors (NR2B)

(TGACCT)

2.1.3.1.1

RXRα (NR2B1)

T01331

2.1.3.1.2

RXRβ (NR2B2)

T01332

F

2.1.3.1.2.1

RXRβ1, isoform long

T02779

2.1.3.1.2.2

RXRβ2, isoform short

T01366

2.1.3.1.3

RXRγ (NR2B3)

T01333

2.1.3.2

Subfamily: HNF-4 (NR2A)

AGTCCAAAGTTCA

2.1.3.2.1

HNF-4α (NR2A1)

T01181

2.1.3.2.1.1

HNF-4α, isoform long

T28928

2.1.3.2.1.2

HNF-4α, isoform short

T26145

2.1.3.2.2

HNF-4γ (NR2A2)

T06235

2.1.3.3

Subfamily: Tailless-like receptors (NR2E)

TGACCTTTGACCT

2.1.3.3.1

Tlx (NR2E1)

T02357

2.1.3.3.2

PNR (NR2E3)

T04861

2.1.3.4

Subfamily: Testicular receptors (NR2C)

TGACCTCTGACCT

2.1.3.4.1

TR2 (NR2C1)

T04847

2.1.3.4.1.1

TR2-11, isoform 1

T11074

2.1.3.4.1.2

TR2-9, isoform 2 (TR2-11-t)

T11075

2.1.3.4.2

TR4 (NR2C2)

T16549

2.1.3.5

Subfamily: COUP-like receptors (NR2F)

TGACCTTTGACCT

2.1.3.5.1

COUP-TFI (NR2F1)

T00994

2.1.3.5.2

COUP-TFII (NR2F2)

T06154

2.1.3.5.3

EAR2 (NR2F6)

T06163

2.1.4

Family: NGFI-B-related receptors (NR4)

TGACCTTT

2.1.4.0.1

NGFI-B (Nur77, NR4A1)

T01348

2.1.4.0.2

NURR1 (NR4A2)

T10226

2.1.4.0.2.1

NURR1, isoform 1

T04312

2.1.4.0.2.2

NURR1, isoform 2 (NURR1A)

T10247

2.1.4.0.3

NOR1 (NR4A3, TEC)

T15963

2.1.4.0.3.1

NOR1, isoform α (long)

T19145

2.1.4.0.3.2

NOR1, isoform β (short, TECΔC)

T19146

2.1.5

Family: FTZ-F1-related receptors (NR5)

TGACCTTG

2.1.5.0.1

FTZ-F1 (SF-1) (NR5A1)

T08551

2.1.5.0.1.1

FTZ-F1, isoform 1

T09519

2.1.5.0.1.2

FTZ-F1, isoform 2

T25132

2.1.5.0.2

LRH-1 (NR5A2)

T04754

2.1.6

Family: GCNF-related receptors (NR6)

TGAACTTGACTTGA

2.1.6.0.1

GCNF (NR6A1)

T15701

F

2.1.6.0.1.1

GCNF, isoform 1

T02772

2.1.6.0.1.2

GCNF, isoform 2

T26225

2.1.6.0.1.3

GCNF, isoform 3

T26226

2.1.7

Family: DAX-related receptors (NR0)

TGACCTT

2.1.7.0.1

DAX1 (NR0B1)

T04677

2.1.7.0.2

SHP (NR0B2)

T05321

2.2

Class: Other C4 zinc finger-type factors

2.2.1

Family: GATA-type zinc fingers

2.2.1.1

Subfamily: Two zinc-finger GATA factors

AGATAA

2.2.1.1.1

GATA-1 (GF-1, EryF1, NF-E1)

T00305

2.2.1.1.1.1

GATA-1, isoform 1

T08291

2.2.1.1.1.2

GATA-1, isoform 2 (GATA-1s)

T26130

2.2.1.1.2

GATA-2

T01302

2.2.1.1.3

GATA-3

T00310

2.2.1.1.4

GATA-4

T02532

2.2.1.1.5

GATA-5

T02685

2.2.1.1.6

GATA-6

T02686

2.2.1.1.6.1

GATA-6, isoform 1

T10208

2.2.1.1.6.2

GATA-6, isoform 2

T26132

2.2.1.2

Subfamily: Single GATA-type zinc-finger

AGATAA

2.2.1.2.1

GATAD1 (ODAG)

T

2.2.1.2.1.1

GATAD1, isoform 1

T

2.2.1.2.1.2

GATAD1, isoform 2

T

2.2.1.2.2

p66-α (GATAD2A)

T

2.2.1.2.3

p66-β (GATAD2B)

T

2.2.1.2.3.1

p66-β, isoform 1

T

2.2.1.2.3.2

p66-β, isoform 2

T

2.2.1.2.4

RERE (ARG, ARP, ATN1L) = 3.5.1.3.7

T

2.2.1.2.5

MTA1 = 3.5.1.3.4

T27821

2.2.1.2.6

MTA2 (MTA1L1, PID) = 3.5.1.3.5

T

2.2.1.2.7

MTA3 = 3.5.1.3.6

T27832

F

2.2.1.2.7.1

MTA3, isoform 1

T27227

2.2.1.2.7.2

MTA3, isoform 2

T27228

2.2.1.2.8

ZGLP1 (GLP-1)

T

2.2.1.2.9

DNMT3A

T27827

2.2.1.2.9.1

DNMT3A, isoform 1

T27196

2.2.1.2.9.2

DNMT3A, isoform 2

T27868

2.2.1.2.10

DNMT3B

T

2.2.1.2.10.1

DNMT3B, isoform 1

T

2.2.1.2.10.2

DNMT3B, isoform 2

T

2.2.1.2.10.3

DNMT3B, isoform 3

T

2.2.1.2.10.4

DNMT3B, isoform 4

T

2.2.1.2.11

DNMT3L

T

2.2.1.2.12

ATRX (RAD54L, XH2)

T

2.2.1.2.13

TRPS1 (GC79) = 2.3.4.0.20

T19349

2.3

Class: C2H2 zinc finger factors

2.3.1

Family: Three-zinc finger Krüppel-related factors

2.3.1.1

Subfamily: Sp1-like factors

GGGGCGGGG

2.3.1.1.1

Sp1

T00752

2.3.1.1.1.1

Sp1, isoform 1

T09118

2.3.1.1.1.2

Sp1, isoform 2 (Sp1-S)

T11472

2.3.1.1.2

Sp2

T06543

2.3.1.1.2.1

Sp2, isoform 1

T10134

2.3.1.1.2.2

Sp2, isoform 2

T10135

2.3.1.1.3

Sp3

T05840

F

2.3.1.1.3.1

Sp3, isoform 1 (L-Sp3)

T19262

2.3.1.1.3.2

Sp3, isoform 2

T19261

2.3.1.1.3.3

Sp3, isoform 3 (M1-Sp3)

T26303

2.3.1.1.4

Sp4

T02414

2.3.1.1.5

Sp5

T19265

2.3.1.1.6

Sp6

T05074

2.3.1.1.7

Sp7

T20132

2.3.1.1.8

Sp8

T27853

2.3.1.1.9

Sp9

T

2.3.1.1.9.1

Sp9, isoform 1

T

2.3.1.1.9.2

Sp9, isoform 2

T

2.3.1.2

Subfamily: Krüppel-like factors

CCACACCCT

2.3.1.2.1

KLF1 (EKLF)

T01676

2.3.1.2.2

KLF2 (LKLF)

T01677

2.3.1.2.3

KLF3 (BKLF)

T10980

2.3.1.2.4

KLF4 (GKLF)

T02450

2.3.1.2.5

KLF5 (CKLF, IKLF, BTEB2)

T05054

2.3.1.2.6

KLF6 (CPBP, BCD1)

T19036

2.3.1.2.7

KLF7 (UKLF)

T26756

F

2.3.1.2.8

KLF8 (BKLF)

T20006

2.3.1.2.9

KLF9 (BTEB1)

T04700

2.3.1.2.10

KLF10 (TIEG1)

T15844

2.3.1.2.11

KLF11 (FKLF, TIEG2)

T17849

2.3.1.2.12

KLF12 (AP-2rep)

T04701

2.3.1.2.13

KLF13 (BTEB3, NSLP1)

T05052

2.3.1.2.14

KLF14 (BTEB5)

T20000

2.3.1.2.15

KLF15 (KKLF)

T20002

2.3.1.2.16

KLF16 (BTEB4, NSLP2)

T05053

2.3.1.2.17

KLF17

T20004

2.3.1.3

Subfamily: EGR factors

GCGTGGGCG

2.3.1.3.1

EGR1 (Krox-24, Zif268)

T10013

2.3.1.3.2

EGR2 (Krox-20)

T00454

2.3.1.3.2.1

EGR2, isoform long

T25981

2.3.1.3.2.2

EGR2, isoform short

T08340

2.3.1.3.3

EGR3 (PILOT)

T05539

2.3.1.3.4

EGR4

T19919

2.3.2

Family: Other factors with up to three adjacent zinc fingers

2.3.2.1

Subfamily: Factors with 2-3 adjacent zinc fingers and a BTB/POZ domain

TCCTGCTA

2.3.2.1.1

ZBTB5 [2]

T19397

2.3.2.1.2

ZBTB8B [2]

T

2.3.2.1.6

ZBTB22 (ZNF297, BING1) [3]

T19377

2.3.2.1.7

ZBTB32 (ZNF538, FAZF) [3]

T15957

2.3.2.1.7.1

ZBTB32, isoform 1

T15956

2.3.2.1.7.2

ZBTB32, isoform 2

T15958

2.3.2.1.8

ZBTB34 [3]

T

2.3.2.1.9

ZBTB37 [3]

T

2.3.2.1.10

ZBTB43 (ZBTB22B, ZNF297B) [3]

T19385

2.3.2.1.11

ZBTB46 (BTBD4, ZNF340) [2]

T

2.3.2.1.11.1

ZBTB46, isoform 1

T

2.3.2.1.11.2

ZBTB46, isoform 2

T

2.3.2.1.12

ZBTB33 (KAISO, ZNF348) [3]

T08299

2.3.2.2

Subfamily: Factors with 2-3 adjacent zinc fingers and a KRAB domain

2.3.2.3

Subfamily: Factors with 2-3 adjacent zinc fingers and a SCAN domain

2.3.2.4

Subfamily: Other three adjacent zinc finger factors

2.3.2.4.1

ZNF414 (Zfp414) [3]

T20584

2.3.2.4.1.1

ZNF414, isoform 1

T20583

2.3.2.4.1.2

ZNF414, isoform 2

T20585

2.3.2.4.2

ZNF511 (Zfp511) [3]

T

2.3.2.4.2.1

ZNF511, isoform 1

T

2.3.2.4.2.2

ZNF511, isoform 2

T

2.3.2.4.3

ZNF580 (Zfp580) [3]

T19527

2.3.2.4.5

ZNF740 (ZFP740) [3]

T16895

2.3.2.4.5.1

ZNF740, isoform 1

T16894

2.3.2.4.5.2

ZNF740, isoform 2

T16897

2.3.2.4.5.3

ZNF740, isoform 3

T16898

2.3.2.4.6

ZFPM2 (ZNF89B, FOG2) = 2.7.2.0.2 [3]

T18922

F

2.3.2.4.6.1

ZFPM2, isoform 1

T18923

2.3.2.4.6.2

ZFPM2, isoform 2

T18924

2.3.2.4.6.3

ZFPM2, isoform 3

T18925

2.3.2.4.7

OSR1 (ODD) [3]

T16932

2.3.2.4.8

OVOL3 (OVL2L) [4]

T

F, ?

2.3.2.4.9

AEBP2 [2]

T18741

2.3.2.4.9.1

AEBP2, isoform 1

T18740

2.3.2.4.9.2

AEBP2, isoform 2

T18736

2.3.2.4.9.3

AEBP2, isoform 3

T18737

2.3.2.4.9.4

AEBP2, isoform 4

T18738

2.3.2.4.9.5

AEBP2, isoform 5

T18739

2.3.3

Family: More than 3 adjacent zinc finger factors

2.3.3.1

Subfamily: GLI-like factors

TGGGTGGTC

2.3.3.1.1

GLI1 [5]

T06385

2.3.3.1.2

GLI2 [5]

T06386

2.3.3.1.3

GLI3 [5]

T06387

2.3.3.1.4

GLIS1 [5]

T06390

2.3.3.1.4.1

GLIS1, isoform 1

T11184

2.3.3.1.4.2

GLIS1, isoform 2

T26134

2.3.3.1.5

GLIS2 (NKL) [5]

T

2.3.3.1.6

GLIS3 (ZNF515) [5]

T17410

2.3.3.1.6.1

GLIS3, isoform 1

T18954

2.3.3.1.6.2

GLIS3, isoform 2

T15909

2.3.3.1.7

ZIC1 (ZNF201) [5]

T04669

2.3.3.1.8

ZIC2 [5]

T04670

2.3.3.1.9

ZIC3 (ZNF203) [5]

T04671

2.3.3.1.9.1

ZIC3, isoform 1 (ZIC3A)

T14517

2.3.3.1.9.2

ZIC3, isoform 2 (ZIC3B)

T26531

2.3.3.1.10

ZIC4 [5]

T

F

2.3.3.1.11

ZIC5 [4]

T

2.3.3.2

Subfamily: Snail-like factors

CACCTG

2.3.3.2.1

SNAI1 [4]

T02333

2.3.3.2.2

SNAI2 (SLUG) [5]

T19238

2.3.3.2.3

SNAI3 (ZNF293) [5]

T10589

2.3.3.2.4

SCRT1 [5]

T20104

2.3.3.2.5

SCRT2 [5]

T20108

2.3.3.3

Subfamily: ZFP91-like factors

2.3.3.3.1

ZFP91 (ZNF757) [5]

T19408

2.3.3.3.1.1

ZFP91, isoform 1

T19407

2.3.3.3.1.2

ZFP91, isoform 2

T26362

2.3.3.3.2

ZNF692 [5]

T19554

2.3.3.3.3

ZNF276 (ZFP276, ZNF477) [5]

T20488

2.3.3.3.3.1

ZNF276, isoform 1

T20487

2.3.3.3.3.2

ZNF276, isoform 2

T20489

2.3.3.3.4

ZNF653 (ZIP67) [5]

T20934

2.3.3.3.4.1

ZNF653, isoform 1

T20933

2.3.3.3.4.2

ZNF653, isoform 2

T20935

2.3.3.4

Subfamily: ZNF280-like zinc finger factors

2.3.3.4.2

ZNF280B (SUHW2, ZNF279, ZNF632, Zfp280b) [4]

T

2.3.3.4.3

ZNF280C (SUHW3, ZNF633, Zfp280c) [5]

T20167

2.3.3.4.4

ZNF280D (SUHW4, ZNF634) [5]

T20177

2.3.3.4.4.1

ZNF280D, isoform 1

T20176

2.3.3.4.4.2

ZNF280D, isoform 2

T20178

2.3.3.4.4.3

ZNF280D, isoform 3

T20179

2.3.3.4.5

POGZ (SUHW5, ZNF280E, ZNF635) [9]

T

2.3.3.5

Subfamily: ZSCAN5-like zinc finger factors

2.3.3.6

Subfamily: ZNF75-like zinc finger factors

2.3.3.7

Subfamily: ZNF705 factors

2.3.3.8

Subfamily: ZBTB7 factors

GACCCC

2.3.3.8.1

ZBTB7A [4]

T08304

2.3.3.8.1.1

ZBTB7A, isoform 1

T19395

2.3.3.8.1.2

ZBTB7A, isoform 2

T08303

2.3.3.8.2

ZBTB7B [4]

T09541

2.3.3.8.3

ZBTB7C [4]

T

2.3.3.9

Subfamily: YY1-like factors

GCCATCTTG

2.3.3.9.1

YY1 [4]

T00278

2.3.3.9.2

YY2 (ZNF631) [4]

T17589

2.3.3.9.3

ZFP42 (REX1, ZNF754) [4]

T00727

2.3.3.10

Subfamily: ZNF24-like factors

TCAT

2.3.3.10.1

ZNF24 (KOX17, ZNF191, ZSCAN3) [4]

T21161

2.3.3.10.6

ZKSCAN1 (KOX18, ZNF139, ZNF36) [6]

T20343

2.3.3.10.6.1

ZKSCAN1, isoform 1

T20342

2.3.3.10.6.2

ZKSCAN1, isoform 2

T20344

2.3.3.11

Subfamily: ZBTB6-like factors

2.3.3.11.1

ZBTB6 (ZID, ZNF482) [4]

T19399

2.3.3.11.2

ZBTB26 (ZNF481) [4]

T

2.3.3.11.3

ZBTB12 (NG35) [4]

T16838

2.3.3.12

Subfamily: PRDM1-like factors

AAGTGAAAGT

2.3.3.12.1

PRDM1 (BLIMP1) [4]

T02316

2.3.3.12.1.1

PRDM1, isoform 1

T14505

2.3.3.12.1.2

PRDM1, isoform 2 (1A)

T26255

2.3.3.12.1.3

PRDM1, isoform 3 (1B)

T26256

2.3.3.12.1.4

PRDM1, isoform 4 (1C)

T26257

2.3.3.12.1.5

PRDM1, isoform 5 (delta exon 7)

T26258

2.3.3.13

Subfamily: ZNF148-like factors

CACCC

2.3.3.13.1

ZNF148 (ZBP89, Zfp148) [4]

T08694

2.3.3.13.2

ZNF281 (GZP1, ZBP99, Zfp281) [4]

T16856

2.3.3.14

Subfamily: ZBTB20-like factors

2.3.3.14.1

ZBTB20 (DPZF, ZNF288, HOF) [5]

T15597

2.3.3.14.1.1

ZBTB20, isoform 1 (HOF-L)

T15595

2.3.3.14.1.2

ZBTB20, isoform 2 (HOF-S)

T15596

2.3.3.14.2

ZBTB45 (ZNF499) [4]

T

2.3.3.15

Subfamily: ZNF524-like factors

2.3.3.15.1

ZNF524 (Zfp524) [4]

T20724

2.3.3.16

Subfamily: ZNF238-like factors

AACATCTGGA

2.3.3.16.1

ZNF238 (RP58, TAZ1, ZBTB18) [4]

T16607

2.3.3.16.2

ZBTB42 [4]

T

2.3.3.16.2.1

ZBTB42, isoform 1

T

2.3.3.16.2.2

ZBTB42, isoform 2

T

2.3.3.17

Subfamily: OVOL-factors

GCGGGGG

2.3.3.17.1

OVOL1 [4]

T08547

2.3.3.17.2

OVOL2 (mOVO, ZNF339) [4]

T08543

2.3.3.17.2.1

OVOL2, isoform 1 (MOVO-A)

T08542

2.3.3.17.2.2

OVOL2, isoform 2 (MOVO-C)

T08545

2.3.3.17.2.3

OVOL2, isoform 3 (MOVO-B)

T08544

2.3.3.18

Subfamily: ZNF56-like factors

2.3.3.19

Subfamily: ZNF500-like factors

2.3.3.19.3

ZKSCAN2 (ZNF694) [6]

T

2.3.3.19.4

ZSCAN29 (ZNF690) [6]

T

2.3.3.20

Subfamily: FEZF factors

2.3.3.20.1

FEZF1 (ZNF312B) [6]

T19931

2.3.3.20.2

FEZF2 (FEZL, ZNF312) [6]

T19936

2.3.3.21

Subfamily: GFI1 factors

AAATCACAGC

2.3.3.21.1

GFI1 (ZNF163) [6]

T06593

2.3.3.21.2

GFI1B [6]

T06585

2.3.3.22

Subfamily: BCL6 factors

CTTTCTAGGAAT

2.3.3.22.1

BCL6B (BAZF, ZNF62) [5]

T16794

2.3.3.22.2

BCL6 (LAZ3, ZBTB27, ZNF51) [6]

T08156

2.3.3.23

Subfamily: ZNF212-like factors

2.3.3.24

Subfamily: MTF1-like factors

TGCACAC

2.3.3.24.1

MTF1 [6]

T00515

2.3.3.24.2

ZNF410 (APA1, Zfp410) [5]

T16880

2.3.3.24.2.1

ZNF410, isoform 1

T16879

2.3.3.24.2.2

ZNF410, isoform 2

T16883

2.3.3.24.2.3

ZNF410, isoform 3

T16884

2.3.3.25

Subfamily: PLAG factors

2.3.3.25.1

PLAGL2 [6]

T18384

2.3.3.25.2

PLAG1 [7]

T21518

2.3.3.25.3

PLAGL1 (LOT1, ZAC) [7]

T10142

2.3.3.26

Subfamily: ZKSCAN3-like factors

TGAGGGG

2.3.3.26.1

ZKSCAN3 (ZFP47, ZNF306, ZNF309, ZSCAN13) [7]

T

2.3.3.26.2

ZKSCAN4 (ZNF307, ZNF427) [7]

T

F

2.3.3.27

Subfamily: ZNF525-like factors

2.3.3.28

Subfamily: ZNF76-like factors

CCCATCATGCCTTGC

2.3.3.28.1

ZNF76 (ZNF523, Zfp523) [7]

T19573

2.3.3.28.1.1

ZNF76, isoform 1

T25999

2.3.3.28.1.2

ZNF76, isoform 2

T26000

2.3.3.28.2

ZNF143 (SBF, STAF) [7]

T18502

2.3.3.28.2.1

ZNF143, isoform 1

T18501

2.3.3.28.2.2

ZNF143, isoform 2

T26365

2.3.3.28.2.3

ZNF143, isoform 3

T26366

2.3.3.29

Subfamily: ZNF652-like factors

2.3.3.29.1

ZNF652 (ZFP652) [9]

T20929

2.3.3.29.1.1

ZNF652, isoform 1

T20928

2.3.3.29.1.2

ZNF652, isoform 2

T20930

2.3.3.30

Subfamily: ZNF350-like factors

TGGgttCAGactTTG

2.3.3.31

Subfamily: ZNF642-like factors

2.3.3.31.4

ZNF583 [12]

T20839

2.3.3.32

Subfamily: ZNF679-like factors

2.3.3.33

Subfamily: ZNF763-like factors

2.3.3.34

Subfamily: ZNF3-like factors

2.3.3.35

Subfamily: ZNF620-like factors

2.3.3.36

Subfamily: ZNF324 factors

2.3.3.37

Subfamily: ZNF362-like factors

2.3.3.38

Subfamily: ZNF282-like factors

TCCACCCC

2.3.3.39

Subfamily: ZNF764-like factors

2.3.3.39.3

ZNF771 [8]

T21051

2.3.3.40

Subfamily: ZNF177-like factors

2.3.3.41

Subfamily: ZNF32-like factors

2.3.3.41.1

ZNF32 (KOX30, Zfp637) [7]

T

2.3.3.41.1.1

ZNF32, isoform 1

T

2.3.3.41.1.2

ZNF32, isoform 2

T

2.3.3.41.2

ZIK1 (ZNF762) [9]

T20335

2.3.3.42

Subfamily: ZNF773-like factors

2.3.3.43

Subfamily: ZNF558-like factors

2.3.3.44

Subfamily: ZNF302-like factors

2.3.3.44.2

ZNF2 (ZNF661, Zfp661) [9]

T21173

2.3.3.45

Subfamily: ZNF562-like factors

2.3.3.46

Subfamily: ZXD-factors

2.3.3.46.2

ZXDB [10]

T

2.3.3.46.3

ZXDC (ZXDL) [10]

T

2.3.3.46.3.1

ZXDC, isoform 1

T

2.3.3.46.3.2

ZXDC, isoform 2

T

2.3.3.46.3.3

ZXDC, isoform 3

T

2.3.3.46.3.4

ZXDC, isoform 4

T

2.3.3.47

Subfamily: ZNF222-like factors

2.3.3.48

Subfamily: ZNF736-like factors

2.3.3.49

Subfamily: ZNF286 factors

2.3.3.50

Subfamily: CTCF-like factors

2.3.3.50.1

CTCF [11]

T02285

2.3.3.50.2

CTCFL (CTCF-T, BORIS) [11]

T

2.3.3.50.2.1

CTCFL, isoform 1

T

2.3.3.50.2.2

CTCFL, isoform 2

T

2.3.3.51

Subfamily: ZNF366-like factors

2.3.3.51.2

ZNF710 (Zfp710) [11]

T21014

2.3.3.51.2.1

ZNF710, isoform 1

T21013

2.3.3.51.2.2

ZNF710, isoform 2

T21015

2.3.3.51.2.3

ZNF710, isoform 3

T21016

2.3.3.52

Subfamily: ZNF322-like factors

2.3.3.52.1

ZNF322A (ZNF322, ZNF388, ZNF489, Zfp322A) [11]

T20185

2.3.3.53

Subfamily: ZNF548-like factors

2.3.3.54

Subfamily: ZNF460-like factors

2.3.3.55

Subfamily: ZNF146-like factors

2.3.3.55.1

ZNF146 [10]

T

2.3.3.55.2

ZNF260 (ZFP260) [13]

T20476

2.3.3.56

Subfamily: ZNF214-like factors

2.3.3.57

Subfamily: ZNF479-like factors

2.3.3.58

Subfamily: ZNF180-like factors

2.3.3.58.3

ZNF436 (Zfp46) [12]

T20615

2.3.3.58.6

ZSCAN2 (ZFP29, ZNF854) [14]

T21249

2.3.3.59

Subfamily: ZNF100-like factors

2.3.3.59.3

ZNF431 (Zfp431, Zfp923) [13]

T23370

2.3.3.60

Subfamily: ZNF98-like factors

2.3.3.61

Subfamily: ZNF343-like factors

2.3.3.62

Subfamily: ZFP2-like factors

2.3.3.62.1

ZFP2 (ZNF751, Mkr2) [13]

T

2.3.3.62.1.1

ZFP2, isoform 1

2.3.3.62.1.2

ZFP2, isoform 2

T02335

2.3.3.63

Subfamily: ZFP30-like factors

2.3.3.63.1

ZFP30 (ZNF745) [13]

T20292

2.3.3.63.2

ZFP82 (ZNF545) [13]

T20313

2.3.3.63.2.1

ZFP82, isoform 1

T20312

2.3.3.63.2.2

ZFP82, isoform 2

T20314

2.3.3.63.2.3

ZFP82, isoform 3

T28055

2.3.3.63.3

ZFP14 (ZNF531) [13]

T

2.3.3.64

Subfamily: ZNF354A-like factors

2.3.3.64.1

ZNF354A (EZNF, HKL1, TCF17, Zfp354a) [13]

T19363

2.3.3.64.2

ZNF354B (Zfp354b) [13]

T20196

2.3.3.65

Subfamily: ZFX/ZFY factors

AGGCCC

2.3.3.65.1

ZFX [13]

T16099

2.3.3.65.2

ZFY-1 [13]

T20325

2.3.3.65.3

ZFY-2 [13]

T20327

2.3.3.66

Subfamily: ZNF689-like factors

2.3.3.66.1

ZNF689 (Zfp689) [12]

T20996

2.3.3.66.2

ZNF672 (Zfp672) [14]

T20968

2.3.3.67

Subfamily: ZFN283-like factors

2.3.3.68

Subfamily: ZFN81-like factors

2.3.3.69

Subfamily: ZFN25-like factors

2.3.3.69.3

ZFP37 [12]

T21364

2.3.3.70

Subfamily: ZFN26-like factors

2.3.3.71

Subfamily: ZFN300-like factors

2.3.3.72

Subfamily: ZFN813-like factors

2.3.3.73

Subfamily: ZNF816A-like factors

2.3.3.74

Subfamily: ZNF442-like factors

2.3.3.75

Subfamily: ZNF432-like factors

2.3.3.76

Subfamily: ZNF665-like factors

2.3.3.77

Subfamily: ZNF595-like factors

2.3.3.78

Subfamily: ZNF14-like factors

2.3.3.79

Subfamily: ZNF841-like factors

2.3.3.80

Subfamily: ZNF99-like factors

2.3.3.0

Subfamily: unclassified

2.3.3.0.1

ZFP161 (ZBTB14, ZNF478, Zfp5)

CTACCTGCACAGTTCACGGA

T02349

2.3.3.0.3

ZNF496 (ZKSCAN17, Zfp496)

T

2.3.3.0.3.1

ZNF496, isoform 1

T

2.3.3.0.3.2

ZNF496, isoform 2

T

2.3.3.0.3.3

ZNF496, isoform 3

T

2.3.3.0.9

OSR2

T16872

2.3.3.0.9.1

OSR2, isoform 1 (OSR2A)

T16871

2.3.3.0.9.2

OSR2, isoform 2 (OSR2B)

T16873

2.3.3.0.13

ZNF22 (KOX15, KROX26, Zfp422)

CAATG

T21157

2.3.3.0.17

ZFP41

T20302

2.3.3.0.20

ZNF18 (KOX11, ZKSCAN6, ZNF535, Zfp18, Zfp535)

T21150

2.3.3.0.21

WT1

CGCCCCCGC

T02351

2.3.3.0.21.1

WT1, isoform 1

T09249

2.3.3.0.21.2

WT1, isoform 2

T19358

2.3.3.0.21.3

WT1, isoform 3

T19356

2.3.3.0.21.4

WT1, isoform 4

T19357

2.3.3.0.21.5

WT1, isoform 5

T26353

2.3.3.0.21.6

WT1, isoform 6

T26354

2.3.3.0.23

PRDM6 (PFM3)

T27850

2.3.3.0.23.1

PRDM6, isoform 1

T27355

2.3.3.0.23.2

PRDM6, isoform 2

T27928

2.3.3.0.23.3

PRDM6, isoform 3

T27929

2.3.3.0.23.4

PRDM6, isoform 4

T27930

2.3.3.0.24

ZNF444 (EZF2, ZSCAN17, Zfp44)

T

2.3.3.0.25

ZNF641 (Zfp641)

T20912

2.3.3.0.25.1

ZNF641, isoform 1

T20911

2.3.3.0.25.2

ZNF641, isoform 2

T20913

2.3.3.0.26

ZNF746 (PARIS, Zfp746)

TATTTTT

T

2.3.3.0.28

ZBTB44 (BTBD15, ZNF851)

T19390

2.3.3.0.28.1

ZBTB44, isoform 1

T19389

2.3.3.0.28.2

ZBTB44, isoform 2

T26360

2.3.3.0.31

ZNF655 (VIK, Zfp655) [6]

T

2.3.3.0.34

ZNF131 [6]

T23316

2.3.3.0.34.1

ZNF131, isoform 1

T23324

2.3.3.0.34.2

ZNF131, isoform 2

T25958

2.3.3.0.34.3

ZNF131, isoform 3

T26363

2.3.3.0.35

PRDM14 [6]

GGTCTCTAA

T

2.3.3.0.37

ZNF575 (Zfp575) [6]

T20823

2.3.3.0.38

ZBTB49 [7]

T

2.3.3.0.38.1

ZBTB49, isoform 1

T

2.3.3.0.38.2

ZBTB49, isoform 2

T

2.3.3.0.38.3

ZBTB49, isoform 3

T

2.3.3.0.39

ZNF691 (Zfp691) [7]

T16890

2.3.3.0.40

ZNF394 (ZKSCAN14, Zfp394, Zfp99) [7]

T20568

2.3.3.0.41

ZNF449 (ZSCAN19, Zfp449) [7]

T

2.3.3.0.42

ZNF498 (ZSCAN25, Zfp498) [7]

T

2.3.3.0.43

ZSCAN30 (ZNF397OS, Zfp397OS) [7]

T

2.3.3.0.47

ZSCAN21 (ZFP38, ZNF38, Zipro1) [7]

T19587

2.3.3.0.54

MYNN (OSZF, ZBTB31) [8]

T20033

2.3.3.0.54.1

MYNN, isoform 1

T20032

2.3.3.0.54.2

MYNN, isoform 2

T20034

2.3.3.0.54.3

MYNN, isoform 3

T20035

2.3.3.0.55

ZBTB24 (ZNF450) [8]

T20221

2.3.3.0.55.1

ZBTB24, isoform 1

T20220

2.3.3.0.55.2

ZBTB24, isoform 2

T20223

2.3.3.0.55.3

ZBTB24, isoform 3

T20222

2.3.3.0.57

ZFP92 [8]

T21421

2.3.3.0.60

ZNF202 (ZKSCAN10, Zfp202) [8]

GGGGTGGGGT

T

2.3.3.0.69

ZNF187 (ZSCAN26, SRE-ZBP, Zfp187) [8]

T16850

2.3.3.0.69.1

ZNF187, isoform 1

T16849

2.3.3.0.69.2

ZNF187, isoform 2

T16851

2.3.3.0.70

ZSCAN22 (HKR2, ZNF50) [8]

T

2.3.3.0.72

ZFP1 (ZNF475) [8]

T20280

2.3.3.0.72.1

ZFP1, isoform 1

T20279

2.3.3.0.72.2

ZFP1, isoform 2

T20281

2.3.3.0.74

ZBTB16 (PLZF, ZNF145) [9]

TAAAGTTTGATCTGTTC

T08243

2.3.3.0.75

GTF3A (TFIIIA) [9]

T19312

2.3.3.0.76

ZFP64 [9]

T19406

2.3.3.0.76.1

ZFP64, isoform 1

T19405

2.3.3.0.76.2

ZFP64, isoform 2

2.3.3.0.76.3

ZFP64, isoform 3 [8]

2.3.3.0.77

ZNF358 (Zfp358) [9]

T

2.3.3.0.79

ZNF263 (FPM315, ZKSCAN12, Zfp263) [9]

GGGAGGAGG

T22394

2.3.3.0.81

ZNF192 (ZKSCAN8, LD5-1, Zfp192) [9]

T23327

2.3.3.0.83

ZNF239 (HOK-2, MOK-2, Zfp239) [9]

T00510

2.3.3.0.84

ZNF664 (ZFOC1, ZNF196, Zfp664) [9]

T20951

2.3.3.0.92

GZF1 (ZBTB23, ZNF336) [10]

TGCGCGTCTATA

T08231

2.3.3.0.93

ZNF408 (PFM14, PRDM17, Zfp408) [10]

T

2.3.3.0.94

ZNF648 (Zfp648) [10]

T

2.3.3.0.95

ZNF768 (Zfp768) [10]

T21043

2.3.3.0.101

ZNF483 (ZKSCAN16) [11]

T

2.3.3.0.102

ZBTB48 (HKR3, ZNF855) [11]

T20247

2.3.3.0.102.1

ZBTB48, isoform 1

T20246

2.3.3.0.102.2

ZBTB48, isoform 2

T20248

2.3.3.0.103

ZNF275 (Zfp275) [11]

T

2.3.3.0.114

ZNF354C (KID3) [11]

CCACC

T20198

2.3.3.0.120

ZSCAN12 (ZNF305, ZNF96) [11]

T21524

2.3.3.0.123

ZBTB40 [12]

T

2.3.3.0.125

ZNF454 (Zfp454) [12]

T

2.3.3.0.148

ZNF329 (Zfp329) [12]

T20524

2.3.3.0.149

ZFP90 (ZNF756) [13]

T20318

2.3.3.0.150

ZNF317 (Zfp317) [13]

T

2.3.3.0.152

MZF1 (ZNF42, ZSCAN6) [13]

AGTGGGGA

T08517

2.3.3.0.157

ZNF879 (Zfp879) [13]

T

2.3.3.0.159

ZNF167 (ZKSCAN7, ZNF448, ZNF64, Zfp167) [13]

T

2.3.3.0.160

ZNF250 (ZNF647, Zfp647) [13]

T19444

2.3.3.0.162

ZFP3 (ZNF752) [13]

T20298

2.3.3.0.166

ZNF311 (ZFP31, Zscan20) [14]

T

2.3.3.0.166.1

ZNF311, isoform 1

T

2.3.3.0.166.2

ZNF311, isoform 2

T

2.3.3.0.167

ZNF551 (KOX23, Zfp551) [14]

T

2.3.3.0.169

ZSCAN10 (ZNF206) [14]

GCGCATGCGC

T18325

2.3.3.0.169.1

ZSCAN10, isoform 1

T18322

2.3.3.0.169.2

ZSCAN10, isoform 2

T18324

2.3.3.0.169.3

ZSCAN10, isoform 3

T18326

2.3.3.0.174

ZNF287 (ZKSCAN13) [14]

T21498

2.3.3.0.179

ZNF667 [15]

T20955

2.3.3.0.192

ZFP28 [15]

T20285

2.3.3.0.192.1

ZFP28, isoform 1

T20284

2.3.3.0.192.2

ZFP28, isoform 2

T20286

2.3.3.0.193

ZNF182 (KOX14, ZNF21, Zfp182) [15]

T20399

2.3.3.0.195

PRDM5 (PFM2) [16]

GGAGAGCAGG

T20084

2.3.3.0.196

RBAK (ZNF769) [16]

T

2.3.3.0.197

ZNF189 (Zfp189) [16]

T

2.3.3.0.215

ZNF569 (Zfp74) [18]

T20803

2.3.3.0.219

ZNF271 (HZF7, ZNF-dp, ZNFEB, Zfp35) [19]

T00921

2.3.3.0.220

ZNF184 (Zfp184) [19]

T20403

2.3.3.0.231

ZFP62 [23]

T

2.3.3.0.231.1

ZFP62, isoform 1

T

2.3.3.0.231.2

ZFP62, isoform 2

T

2.3.3.0.231.3

ZFP62, isoform 3

T

2.3.4

Family: Factors with multiple dispersed zinc fingers

2.3.4.1

Subfamily: ZNF417-like factors

2.3.4.2

Subfamily: ZNF219-like factors

CCCCCA

2.3.4.2.1

ZNF219 (Zfp219) [2+1+2+1]

T

2.3.4.2.2

ZNF536 (Zfp536) [2+4+1+2]

T20746

2.3.4.2.3

ZNF516 (Zfp516) [2+5+1+1+1]

T20711

2.3.4.2.4

ZNF217 (ZABC1) [1+3+1+2]

T

2.3.4.3

Subfamily: Sal-like factors

2.3.4.3.1

SALL1 (Spalt-1, Sal-1, ZNF794) [2+3+2+2]

T19221

2.3.4.3.2

SALL2 (Spalt-2, Sal-2, ZNF795) [2+3+2]

T19225

2.3.4.3.3

SALL3 (Sal-3, ZNF796) [2+3+2+2]

T20099

2.3.4.3.3.1

SALL3, isoform 1 [2+3+2+2]

T20098

2.3.4.3.3.2

SALL3, isoform 2 [2+3]

T20100

2.3.4.3.4

SALL4 (ZNF797) [2+3+2+2]

T19229

2.3.4.3.4.1

SALL4, isoform 1 (Sall4a) [2+3+2+2]

T19228

2.3.4.3.4.2

SALL4, isoform 2 (Sall4b) [2]

T26286

2.3.4.3.4.3

SALL4, isoform 3 (Sall4c) [2]

T26287

2.3.4.4

Subfamily: Ikaros

TTGGGAAT

2.3.4.4.1

IKZF1 (IK1, IKAROS, Lyf-1, ZNFN1A1) [4+2]

T00479

2.3.4.4.1.1

IKZF1, isoform I [3+2]

T01469

2.3.4.4.1.2

IKZF1, isoform II [3+2]

T01470

2.3.4.4.1.3

IKZF1, isoform III [3+2]

T01471

2.3.4.4.1.4

IKZF1, isoform IV [1+2]

T01472

2.3.4.4.1.5

IKZF1, isoform V [2]

T01473

2.3.4.4.1.6

IKZF1, isoform VI

T19007

2.3.4.4.2

IKZF2 (HELIOS, ZNFN1A2, Zfpn1a2) [4+2]

T06012

2.3.4.4.2.1

IKZF2, isoform B

T11158

2.3.4.4.2.2

IKZF2, isoform A [3+2]

T19008

2.3.4.4.3

IKZF3 (Aiolos, ZNFN1A3) [4+2]

T05979

2.3.4.4.4

IKZF4 (EOS, ZNFN1A4, Zfpn1a4) [4+2]

T19017

2.3.4.4.4.1

IKZF4, isoform 1

T19016

2.3.4.4.4.2

IKZF4, isoform 2

T26152

2.3.4.4.4.3

IKZF4, isoform 3

T26153

2.3.4.4.4.4

IKZF4, isoform 4

T26154

2.3.4.4.5

IKZF5 (Pegasus, ZNFN1A5, Zfpn1a5) [3+2]

T19022

2.3.4.4.5.1

IKZF5, isoform 1

T19020

2.3.4.4.5.2

IKZF5, isoform 2

T19021

2.3.4.4.5.3

IKZF5, isoform 3

T26155

2.3.4.5

Subfamily: HIV EP-factors

GGGACTTTCC

2.3.4.5.1

HIV-EP1 (ZNF40, PRDII-BF1, MBP-1, CIRIP, GAAP) [2+1+2]

T00007

F

2.3.4.5.2

HIV-EP2 (MBP-2, ZNF40B) [2+2]

T16993

2.3.4.5.3

HIV-EP3 (KBP1, KRC, ZAS3) [2+1+2]

T02315

2.3.4.6

Subfamily: ZBTB1-like factors

2.3.4.6.1

ZBTB1 [1+1+6]

T20252

2.3.4.6.2

ZBTB2 (ZNF437) [1+3]

T

2.3.4.6.3

ZBTB25 (KUP, ZNF46) [1+1]

T

2.3.4.7

Subfamily: RLF-like factors

2.3.4.7.1

RLF [1+5+1+2+4+1]

F

T

2.3.4.7.2

ZNF292 (Zfp292) [1+5+1+1+2+4+1]

T

2.3.4.7.2.1

ZNF292, isoform 1

T

2.3.4.7.2.2

ZNF292, isoform 2

T

2.3.4.7.3

ZNF654 (Zfp654) [1+4]

T20939

2.3.4.8

Subfamily: MAZ-like factors

GGGGAGGG

2.3.4.8.1

MAZ (Zif87, ZNF801) [1+5]

T02303

2.3.4.8.2

VEZF1 (DB1, ZNF161) [1+5]

T10444

2.3.4.8.3

PATZ1 (RIAZ, ZBTB19, ZNF278, ZSG) [1+5+1]

T04796

2.3.4.9

Subfamily: ZNF532-like factors

2.3.4.9.1

ZNF532 (Zfp532) [1+6+3+2]

T20741

2.3.4.9.1.1

ZNF532, isoform 1

T20740

2.3.4.9.1.2

ZNF532, isoform 2

T20742

2.3.4.9.2

ZNF592 (Zfp592) [2+6+3+2]

T19534

2.3.4.9.3

ZNF687 (Zfp687) [1+5+2+2]

T20988

2.3.4.9.3.1

ZNF687, isoform 1

T20987

2.3.4.9.3.2

ZNF687, isoform 2 [1+5+2]

T20989

2.3.4.9.3.3

ZNF687, isoform 3 [1+5+2]

T20990

2.3.4.10

Subfamily: ZNF512-factors

2.3.4.10.1

ZNF512 (Zfp512) [1+1+2]

T20697

2.3.4.10.2

ZNF512B (Zfp512b) [2+3+2]

F

T

2.3.4.11

Subfamily: ZNF658-factors

2.3.4.12

Subfamily: ZNF423-like factors

GCACCCAAGGGTGC

2.3.4.12.1

ZNF423 (OAZ, Zfp423) [1+7+5+7+10]

T06599

2.3.4.12.1.1

ZNF423, isoform 1

T15869

2.3.4.12.1.2

ZNF423, isoform 2

T15870

2.3.4.12.2

ZNF521 (EHZF, LIP3, Zpf521) [1+7+5+7+5+5]

T20719

2.3.4.12.2.1

ZNF521, isoform 1

T20718

2.3.4.12.2.2

ZNF521, isoform 2

T20720

2.3.4.13

Subfamily: ZNF639-like factors

2.3.4.13.1

ZNF639 (ZASC1, Zfp639) [4+4]

T

2.3.4.13.2

ZNF711 (CMPX1, ZNF6, Zfp711) [1+10]

T

2.3.4.14

Subfamily: Evi-1-like factors

ACAAGATAA

2.3.4.14.1

EVI-1 (MECOM) [7+3]

T00273

2.3.4.14.1.1

EVI-1, isoform 1

T10211

2.3.4.14.1.2

EVI-1, isoform 2

T25985

2.3.4.14.2

PRDM16 (MEL1, PFM13) [7+3]

T27849

2.3.4.14.2.1

PRDM16, isoform 1

T27353

2.3.4.14.2.2

PRDM16, isoform 2 (MEL1L)

T27927

2.3.4.14.2.3

PRDM16, isoform 3

T27354

2.3.4.15

Subfamily: BCL11

2.3.4.15.1

BCL11A (CTIP1, EVI9, ZNF856) [1+2]

T27831

2.3.4.15.1.1

BCL11A, isoform 1 (a) [1+2]

T27221

2.3.4.15.1.2

BCL11A, isoform 2 (b) [2]

T27873

2.3.4.15.1.3

BCL11A, isoform 3 (c) [1]

T27874

2.3.4.15.1.4

BCL11A, isoform 4 [2]

T27875

2.3.4.15.1.5

BCL11A, isoform 5 [1]

T27222

2.3.4.15.1.6

BCL11A, isoform 6 [1]

T27876

2.3.4.15.1.7

BCL11A, isoform 7 [0]

T27877

2.3.4.15.1.8

BCL11A, isoform 8 [2]

T27878

2.3.4.15.2

BCL11B (CTIP2, RIT1) [1+2+3]

T

2.3.4.15.2.1

BCL11B, isoform 1 (α)

T

2.3.4.15.2.2

BCL11B, isoform 2 (β)

T

2.3.4.15.2.3

BCL11B, isoform 3 (γ)

T

2.3.4.15.3

ZNF296 (ZNF342) [1+2+3]

T

2.3.4.16

Subfamily: Insulinoma-associated proteins

2.3.4.16.1

INSM1 (IA-1) [2+1+2]

T16447

2.3.4.16.2

INSM2 (IA-6) [2+3]

T21510

2.3.4.17

Subfamily: Hypermethylated in Cancer proteins

GGGTGCCCGG

2.3.4.17.1

HIC1 (ZBTB29) [1+4]

T06430

F

2.3.4.17.2

HIC2 (HRG22, ZBTB30) [1+4]

T18974

2.3.4.17.2.1

HIC2, isoform 1

T18976

2.3.4.17.2.2

HIC2, isoform 2 [1+1]

T18975

2.3.4.18

Subfamily: ZNF518

2.3.4.18.1

ZNF518A (Zfp518a) [4+1]

T

2.3.4.18.2

ZNF518B (Zfp518b) [2+1]

T21344

2.3.4.19

Subfamily: Basonuclin

2.3.4.19.1

BNC1 [2+2+2]

T05192

2.3.4.19.2

BNC2 [1+1+2]

T

2.3.4.19.2.1

BNC2, isoform 1

T

2.3.4.19.2.2

BNC2, isoform 2

T

2.3.4.20

Subfamily: TRERF1-like factors

2.3.4.20.1

TRERF1 (BCAR2, RAPA, TREP132) = 3.5.1.3.9 [1+1+1]

T16489

2.3.4.20.1.1

TRERF1, isoform 1

T16488

2.3.4.20.1.2

TRERF1, isoform 2

T16490

2.3.4.20.1.3

TRERF1, isoform 3 [1]

T16491

2.3.4.20.1.4

TRERF1, isoform 4

T16492

2.3.4.20.2

ZNF541 (Ship1, Zfp541) [3+1+1] = 3.5.1.3.10

T

2.3.4.20.2.1

ZNF541, isoform 1

T

2.3.4.20.2.2

ZNF541, isoform 2

T

2.3.4.21

Subfamily: HINFP-like factors

CGGACGTT

2.3.4.21.1

HINFP (MIZF, ZNF743) [1+8]

T

2.3.4.21.2

ZFAT (ZFAT1, ZNF406, Zfp406) [1+1+7+10]

T20270

2.3.4.21.2.1

ZFAT, isoform 1

T20269

2.3.4.21.2.2

ZFAT, isoform 2

T20271

2.3.4.22

Subfamily: ZNF526-like factors

2.3.4.22.1

ZNF526 (Zfp526) [1+2+1+9]

T20728

2.3.4.22.1.1

ZNF526, isoform 1

T20727

2.3.4.22.1.2

ZNF526, isoform 2 [1+2+1+4]

T20729

2.3.4.22.2

ZNF574 [3+1+4+8+4]

T20819

2.3.4.23

Subfamily: ZNF319-like factors

2.3.4.23.1

ZNF319 (Zfp319) [3+13]

T20516

2.3.4.23.2

ZNF786 (Zfp786) [2+14]

T21088

2.3.4.24

Subfamily: ZNF134-like factors

2.3.4.25

Subfamily: ZNF37A-like factors

2.3.4.25.3

ZNF248 (Zfp248) [1+7]

T

2.3.4.25.4

ZNF334 (Zfp334) [9+5]

T

2.3.4.25.5

ZNF382 (KS1, Zfp382) [1+9]

T20560

2.3.4.0

Subfamily: unclassified

2.3.4.0.1

CASZ1 (CST, SRG, ZNF693) [3+1+1+3]

T19862

2.3.4.0.1.1

CASZ1, isoform 1

T19861

2.3.4.0.1.2

CASZ1, isoform 2 [3+1]

T19863

2.3.4.0.2

ZNF335 (NIF-1, Zfp335) [1+8+4]

T

2.3.4.0.3

PRDM8 (PFM5) [1+2]

T20089

2.3.4.0.4

WIZ (ZNF803) [4+2+1+1+1+1+1]

T

2.3.4.0.4.1

WIZ, isoform L

T

2.3.4.0.4.2

WIZ, isoform S [1+1+1+1+1+1]

T

2.3.4.0.4.3

WIZ, isoform 2 [1+1+1+1+1]

T

2.3.4.0.4.4

WIZ, isoform 3 [4]

T

2.3.4.0.5

ZNF469 [1+1+3]

F

T

2.3.4.0.6

ZFPM1 (FOG1, ZFN89A) = 2.7.2.0.1 [3+1]

T02334

2.3.4.0.7

ZBTB4 (KAISO-L1) [1+3+2]

T

2.3.4.0.8

ZBTB38 [2+3+5]

T

2.3.4.0.9

ZBTB39 [2+3+3]

T

2.3.4.0.10

ZNF295 (ZBTB21) [2+1+2+2+1]

T

2.3.4.0.11

ZNF827 [3+4+2]

T21121

2.3.4.0.11.1

ZNF827, isoform 1

T21120

2.3.4.0.11.2

ZNF827, isoform 2 [2]

T21122

2.3.4.0.12

PRDM13 (PFM10) [1+3]

T

2.3.4.0.12.1

PRDM13, isoform 1

T

2.3.4.0.12.2

PRDM13, isoform 2

T

2.3.4.0.13

ZNF646 (PFM10, Zfp646) [1+3]

T

F

2.3.4.0.14

ZNF579 (Zfp579) [3+2+3]

T20833

2.3.4.0.15

RREB1 (FINB, Zep-1, LZ321) [3+2+1+5+1+1+2]

CCCCAAACACCCCC

T17652

2.3.4.0.15.1

RREB1, isoform 1

T17651

2.3.4.0.15.2

RREB1, isoform 2 [3+2+1+5+1+1+2]]

T17653

2.3.4.0.15.3

RREB1, isoform 3 [3+2+1+5+2+1+2]

T17654

2.3.4.0.15.4

RREB1, isoform 4 [3+2+1+5+1]

T17655

2.3.4.0.16

PRDM2 (G3B, MTB-ZF, MTE-BP, KMT8, RIZ) [2+1+3+1+1]

GTCATATGAC

T

2.3.4.0.17

ZNF800 (Zfp800) [1+3+2+1]

T21110

2.3.4.0.18

ZNF618 [3+1]

T21454

F

2.3.4.0.18.1

ZNF618, isoform 1

T21453

2.3.4.0.18.2

ZNF618, isoform 2 [3]

T21455

2.3.4.0.19

ZNF277 (NRIF4, ZNF277P, Zfp277) [1+1]

T

2.3.4.0.20

TRPS1 (GC79) = 2.2.1.2.13 [1+1+3+2]

T19349

2.3.4.0.21

ZNF451 (COASTER, Zfp451) [1+3+2+3+2]

T19504

2.3.4.0.22

ZNF438 [3+1]

T

2.3.4.0.23

PEG3 (ZSCAN24) [4+1+5+2]

T

2.3.4.0.23.1

PEG3, isoform 1

2.3.4.0.23.2

PEG3, isoform 2 [2]

T22527

2.3.4.0.24

ZNF507 (Zfp507) [2+1+3+2+1]

T20688

2.3.4.0.25

ZNF236 (Zfp236) [9+4+4+4+4+5]

T

2.3.4.0.26

ZNF770 (Zfp770) [3+3+1+2+2]

T21047

2.3.4.0.27

REST (NRSF, XBR) [1+7+1]

TTCAGCACCACGGACAGCGCC

T05934

2.3.4.0.27.1

REST, isoform 1

T09307

2.3.4.0.27.2

REST, isoform 2 (N16, REST4) [1+4]

T10486

2.3.4.0.27.3

REST, isoform 3 (N28) [1+4]

T26267

2.3.4.0.28

ZFP57 (ZNF698) [4+3]

TTCAGCACCACGGACAGCGCC

T20308

2.3.4.0.28.1

ZFP57, isoform 1

T20307

2.3.4.0.28.2

ZFP57, isoform 2

T20309

2.3.4.0.29

ZNF8 (HF.18, Zfp128) [6+1]

T22794

2.3.4.0.30

ZNF597 (Zfp597) [4+3]

T

2.3.4.0.31

PRDM4 (PFM1) [1+5]

T18699

2.3.4.0.32

PRDM15 (ZNF298) [1+15]

T

2.3.4.0.33

ZBTB41 (FRBZ1) [1+13]

T20243

2.3.4.0.34

PRDM10 (PFM7, TRIS) [1+9]

T

2.3.4.0.34.1

PRDM10, isoform 1

2.3.4.0.34.2

PRDM10, isoform 2 [0]

2.3.4.0.35

ZNF341 (Zfp341) [1+2+9]

T

F

2.3.4.0.36

ZNF513 (Zfp513) [3+5]

T20703

2.3.4.0.36.1

ZNF513, isoform 1

T20702

2.3.4.0.36.2

ZNF513, isoform 2

T20704

2.3.4.0.37

ZNF142 (Zfp142) [14+17]

T

2.3.4.0.38

FIZ1 (ZNF798) [4+2+5]

T

2.3.4.0.39

ZNF628 (Zfp628) [7+2+6]

CAAGGTTGGTTGC

T08324

2.3.4.0.39.1

ZNF628, isoform 1

T08319

2.3.4.0.39.2

ZNF628, isoform 2 [7]

T26369

2.3.4.0.40

ZNF784 (Zfp784) [3+3]

T21081

2.3.4.0.41

ZNF697 (Zfp697) [1+10]

T21002

2.3.4.0.42

ZKSCAN5 (ZFP95) [4+9]

T21526

2.3.4.0.43

ZNF316 (Zfp316) [6+9]

T20264

2.3.4.0.44

ZNF775 (Zfp775) [4+4+3]

T21063

2.3.4.0.45

ZNF467 (Zfp467) [7+5]

T19511

2.3.4.0.46

ZNF787 (TTF-I-IP20, Zfp787) [5+2]

T21090

2.3.4.0.48

ZNF48 (ZNF553, Zfp48, Zfp553) [8+2+2]

T21192

2.3.4.0.49

ZNF629 (ZNF65, Zfp629) [15+3+1]

T20905

2.3.4.0.50

ZNF668 (Zfp668) [13+3]

T20959

2.3.4.0.53

ZNF445 (ZKSCAN15, ZNF168, Zfp445) [12+2]

T20627

2.3.4.0.56

ZSCAN20 (KOX29, ZNF31, ZNF360) [4+6]

T

2.3.4.0.56.1

ZSCAN20, isoform 1

T

2.3.4.0.56.2

ZSCAN20, isoform 2

T

2.3.4.0.64

ZNF426 (Zfp426) [1+11]

T19487

2.3.4.0.65

ZFP112 (ZNF112, ZNF228) [1+16]

T21386

2.3.4.0.65.1

ZFP112, isoform 1

T21385

2.3.4.0.65.2

ZFP112, isoform 2

T21387

2.3.4.0.67

ZNF606 (ZNF328, Zfp606) [2+14]

T

2.3.4.0.71

PRDM9 (PFM6) [1+12]

T

2.3.4.0.71.1

PRDM9, isoform 1 (Meisetz)

2.3.4.0.71.2

PRDM9, isoform 2 (Meisetz-S1) [0]

2.3.4.0.71.3

PRDM9, isoform 3 (Meisetz-S2) [0]

2.3.4.0.71.4

PRDM9, isoform 4 [0]

2.3.4.0.72

ZBTB17 (MIZ1, ZNF151, ZNF60) [12+1]

T17704

2.3.4.0.73

ZNF407 (Zfp407) [3+3+1+2+2+11]

T

2.3.4.0.74

E4F1 (p120E4F, p50E4F) [3+6]

TACGTCAC

T02287

2.3.4.0.74.1

E4F1, isoform 1

T14957

2.3.4.0.74.2

E4F1, isoform 2

T26091

2.3.4.0.74.3

E4F1, isoform 3

T26092

2.3.4.0.74.4

E4F1, isoform 4 [3+1]

T26093

2.3.4.0.74.5

E4F1, isoform 5 [2+6]

T26094

2.3.4.0.75

ZNF462 (Zfp462) [1+2+2+1+3+1+1+3+2+1+4+5+1]

T

2.3.4.0.76

ZNF644 (ZEP2, Zfp644) [5+1+1]

T

2.3.4.0.77

ADNP (ADNP1) = 3.1.8.1.1 [4+3+2]

T21522

2.3.4.0.78

ADNP2 (ZNF508) = 3.1.8.1.2 [1+1+1+1]

T19732

2.3.5

Family: BED zinc finger factors

TGTCGCGACA

2.3.5.0.3

ZBED3

T

2.3.5.0.4

ZBED4

T

2.3.5.0.6

ZBED6 (MGR)

T17368

2.3.5.0.6.1

ZBED6, isoform 1 (a)

T17346

2.3.5.0.6.2

ZBED6, isoform 2 (b)

T17365

2.4

Class: C6 zinc cluster factors

2.5

Class: DM-type intertwined zinc finger factors

2.5.1

Family: DMRT

TGATACATTGTTGC

2.5.1.0.1

DMRT1

T10713

2.5.1.0.1.1

DMRT1, isoform 1 (a)

T10712

2.5.1.0.1.2

DMRT1, isoform 2 (b)

T26413

2.5.1.0.1.3

DMRT1, isoform 3 (d)

T26414

2.5.1.0.1.4

DMRT1, isoform 4 (c)

T26415

2.5.1.0.2

DMRT2

T10722

2.5.1.0.3

DMRT3

T10724

2.5.1.0.4

DMRTA1 (DMRT4)

T10728

2.5.1.0.5

DMRTA2 (DMRT5)

T10732

2.5.1.0.6

DMRTB1

T10730

2.5.1.0.7

DMRTC2

T10726

2.5.1.0.8

DMRTC1a (no DM domain!)

T

2.5.1.0.8.1

DMRTC1a, isoform 1 (c)

T

2.5.1.0.8.2

DMRTC1a, isoform 2 (b)

T

2.5.1.0.8.3

DMRTC1a, isoform 3 (a)

T

2.5.1.0.9

DMRTC1b (no DM domain!)

T

2.5.1.0.10

DMRTC1c (no DM domain!)

T

2.6

Class: CXXC zinc finger factors

2.6.1

Family: CpG-binding proteins

2.6.1.0.1

CpG-binding protein (CXXC1, CFP1, CGBP, PCCX1, PHF18)

T19901

2.6.1.0.2

MBD1 (CXXC3, PCM1)

T

2.6.1.0.2.1

MBD1, isoform 1 (a)

T

2.6.1.0.2.2

MBD1, isoform 2 (b)

T

2.6.1.0.2.3

MBD1, isoform 3 (d)

T

2.6.1.0.2.4

MBD1, isoform 4

T

2.6.1.0.2.5

MBD1, isoform 5

T

2.6.1.0.3

TET1 (CXXC6, LCX)

T

2.6.1.0.4

MLL (CXXC7, ALL1, HRX, HTRX, KMT2A, MLL1, TRX1)

T27835

2.6.1.0.4.1

MLL, isoform 1

T27239

2.6.1.0.4.2

MLL, isoform 14P-18B

T27889

2.6.1.0.5

KDM2A (CXXC8, FBL7, FBXL11, JHDM1A)

T27843

2.6.1.0.5.1

KDM2A, isoform 1

T27346

2.6.1.0.5.2

KDM2A, isoform 2

T27920

2.6.1.0.5.3

KDM2A, isoform 3

T27921

2.6.1.0.6

DNMT1 (CXXC9, AIM, DNMT)

T27826

2.6.1.0.6.1

DNMT1, isoform 1 (long)

T27185

2.6.1.0.6.2

DNMT1, isoform 2 (short)

T27865

2.6.1.0.7

MLL2 (HRX2, KMT2B, WBP7, MLL4, TRX2)

T19083

2.7

Class: C2HC zinc finger factors

2.7.1

Family: Myelin transcription factor-related proteins

AAGTT

2.7.1.0.1

MYT1 (MyT1, MTF1, MYTI, PLPB1) [7]

T22947

2.7.1.0.1.1

MYT1, isoform 1 (NZF-2b)

T25788

2.7.1.0.1.2

MYT1, isoform 2 (NZF-2a) [6]

T25789

2.7.1.0.1.3

MYT1, isoform 3 [6]

T26205

2.7.1.0.2

MYT1L (MyT1L, NZF-1) [6]

T27828

2.7.1.0.2.1

MYT1L, isoform 1

T27211

2.7.1.0.2.2

MYT1L, isoform 2

T27212

2.7.1.0.2.3

MYT1L, isoform 3 [0]

2.7.1.0.2.4

MYT1L, isoform 4 [2]

2.7.1.0.3

ST18 (ZNF387, NZF-3) [6]

T

2.7.2

Family: Friend of GATA proteins

2.7.2.0.1

FOG1 (ZFPM1, ZFN89A) [5] = 2.3.4.0.6

T02334

2.7.2.0.2

FOG2 (ZFPM2, ZFN89B) [5] = 2.3.2.4.6

T18922

F

2.7.3

Family: Histone acetyltransferases with C2HC zinc finger

2.7.3.0.1

MYST1 (KAT8, TIP60 protein 1) [1]

T27842

2.7.3.0.1.1

MYST1, isoform 1

T27345

2.7.3.0.1.2

MYST1, isoform 2 [0]

T27919

2.7.3.0.2

MYST2 (KAT7, TIP60 protein 2, HBO1, HBOa) [1]

T

2.7.3.0.2.1

MYST2, isoform 1

T

2.7.3.0.2.2

MYST2, isoform 2

T

2.7.3.0.2.3

MYST2, isoform 3

T

2.7.3.0.2.4

MYST2, isoform 4

T

2.7.3.0.2.5

MYST2, isoform 5

T

2.7.3.0.3

MYST3 (KAT6A, TIP60 protein 3, RUNXBP2, ZNF220, MOZ) [1]

T

2.7.3.0.4

MYST4 (KAT6B, TIP60 protein 4, MORF, MOZ2) [1]

T

2.7.3.0.4.1

MYST4, isoform 1

T

2.7.3.0.4.2

MYST4, isoform 2

T

2.7.3.0.5

KAT5 (HTATIP, TIP60) [1]

T27824

2.7.3.0.5.1

KAT5, isoform 1

T27282

2.7.3.0.5.2

KAT5, isoform 2

T27283

2.7.3.0.5.3

KAT5, isoform 3

T27284

2.7.3.0.5.4

KAT5, isoform 4

T27944

2.7.4

Family: Lethal(3)malignant brain tumor-related proteins

2.7.4.0.1

L3MBTL1 (L3MBT, L3MBTL) [1]

T

2.7.5

Family: LYAR-related proteins

2.7.5.0.1

LYAR (PNAS-5) [2]

T

2.8

Class: C3H zinc finger factors

2.8.1

Family: ZC3H8-related factors

2.8.1.0.1

ZC3H8 (ZC3HDC8, FLIZ1) [3]

T

2.8.1.0.2

ZC3H4 [3]

T

2.8.1.0.2.1

ZC3H4, isoform 1

T

2.8.1.0.2.2

ZC3H4, isoform 2

T

2.8.1.0.3

ZC3H6 (ZC3HDC6) [3]

T

2.8.1.0.3.1

ZC3H6, isoform 1

2.8.1.0.3.2

ZC3H6, isoform 2 [0]

2.8.2

Family: ZGPAT-related factors

2.8.2.0.1

ZGPAT (GPATC6, GPATCH6, ZC3H9, ZC3HDC9, ZIP) [1]

T27855

2.8.3

Family: RC3H-related factors

2.8.3.0.1

RC3H2 (Roquin-2, MNAB, RNF164) [1]

T

2.8.4

Family: CNOT4-related factors

2.8.4.0.1

CNOT4 (NOT4) [1]

T27838

2.8.4.0.1.1

CNOT4, isoform 1

T27257

2.8.4.0.1.2

CNOT4, isoform 2

T27258

2.8.4.0.1.3

CNOT4, isoform 3

T27940

2.9

Class: C2CH THAP-type zinc finger factors

2.9.1

Family: THAP-related factors

TTGCCCGTACT

2.9.1.0.1

THAP1

T

2.9.1.0.2

THAP2

T

2.9.1.0.3

THAP3

T

2.9.1.0.4

THAP4 (CGI-36, PP238)

T

2.9.1.0.4.1

THAP4, isoform 1

T

2.9.1.0.4.2

THAP4, isoform 2

T

2.9.1.0.7

THAP7

T

2.9.1.0.11

THAP11 (HRIHFB2206)

T

2.9.1.0.12

PRKRIR (P52RIPK, DAP4, THAP0)

T

3

Superclass: Helix-turn-helix domains

3.1

Class: Homeo domain factors

3.1.1

Family: HOX-related factors

3.1.1.1

Subfamily: HOX1

TAATTA

3.1.1.1.1

Hox-A1 (HOX1F, ERA-1)

T01696

3.1.1.1.1.1

Hox-A1, isoform 1 (ERA-1-993)

3.1.1.1.1.2

Hox-A1, isoform 2 (ERA-1-399)

3.1.1.1.2

Hox-B1 (HOX2I)

T01720

3.1.1.1.3

Hox-D1 (HOX4G)

T01750

3.1.1.2

Subfamily: HOX2

TAATTA

3.1.1.2.1

Hox-A2 (HOX1K)

T13907

3.1.1.2.2

Hox-B2 (HOX2H)

T19758

3.1.1.3

Subfamily: HOX3

TAATTA

3.1.1.3.1

Hox-A3 (HOX1E)

T00378

3.1.1.3.2

Hox-B3 (HOX2G)

T01724

3.1.1.3.3

Hox-D3 (HOX4A)

T03339

3.1.1.4

Subfamily: HOX4

TTAATTAA

3.1.1.4.1

Hox-A4 (HOX1D)

T01701

F

3.1.1.4.2

Hox-B4 (HOX2F)

T01728

3.1.1.4.3

Hox-C4 (HOX3E)

T03340

3.1.1.4.4

Hox-D4 (HOX4B)

T

3.1.1.5

Subfamily: HOX5

TAATTA

3.1.1.5.1

Hox-A5 (HOX1C)

T00377

3.1.1.5.2

Hox-B5 (HOX2A)

T13933

3.1.1.5.3

Hox-C5 (HOX3D)

T03351

3.1.1.6

Subfamily: HOX6-7

TAATTA

3.1.1.6.1

Hox-A6 (HOX1B)

T03338

3.1.1.6.2

Hox-B6 (HOX2B)

T01733

3.1.1.6.3

Hox-C6 (HOX3C)

T25653

3.1.1.6.3.1

Hox-C6, isoform 1 (PRII)

T01744

3.1.1.6.3.2

Hox-C6, isoform 2 (PRI)

T01743

3.1.1.6.4

Hox-A7 (HOX1A)

T01278

3.1.1.6.5

Hox-B7 (HOX2C)

T01735

3.1.1.7

Subfamily: HOX8

GTAATTA

3.1.1.7.1

Hox-B8 (HOX2D)

T01737

3.1.1.7.2

Hox-C8 (HOX3A)

T01749

3.1.1.7.3

Hox-D8 (HOX4E)

T

F

3.1.1.8

Subfamily: HOX9-13

TCGTAAA

3.1.1.8.1

Hox-A9 (HOX1G)

T14354

3.1.1.8.1.1

Hox-A9, isoform 1

T01710

3.1.1.8.1.2

Hox-A9, isoform 2 (T)

T04132

3.1.1.8.2

Hox-B9 (HOX2E)

T01739

3.1.1.8.3

Hox-C9 (HOX3B)

T03349

3.1.1.8.4

Hox-D9 (HOX4C)

T01755

3.1.1.8.5

Hox-A10 (HOX1H)

T01715

3.1.1.8.5.1

Hox-A10, isoform 1

T09504

3.1.1.8.5.2

Hox-A10, isoform 2

T09505

3.1.1.8.6

Hox-C10 (HOX3I)

T03350

3.1.1.8.7

Hox-D10 (HOX4D, HOX4E)

T01757

3.1.1.8.8

Hox-A11 (HOX1I)

T01717

3.1.1.8.9

Hox-C11 (HOX3H)

T03352

3.1.1.8.10

Hox-D11 (HOX4F)

T01760

3.1.1.8.11

Hox-C12 (HOX3F)

T03353

3.1.1.8.12

Hox-D12 (HOX4H)

T01763

3.1.1.8.13

Hox-A13 (HOX1J)

T03337

F

3.1.1.8.14

Hox-B13

T03802

3.1.1.8.15

Hox-C13 (HOX3G)

T03354

3.1.1.8.16

Hox-D13 (HOX4I)

T01765

3.1.1.9

Subfamily: CDX (Caudal type homeobox)

GGTAATAAA

3.1.1.9.1

CDX-1

T01999

F

3.1.1.9.2

CDX-2 (CDX-3)

T02002

3.1.1.9.3

CDX-4

T03245

3.1.1.10

Subfamily: EVX (Even-skipped homolog)

CTAATTAG

3.1.1.10.1

EVX-1

T02023

3.1.1.10.2

EVX-2

T16867

3.1.1.11

Subfamily: GBX (Gastrulation brain homeobox)

CTAATTAG

3.1.1.11.1

GBX-1

T16868

3.1.1.11.2

GBX-2

T04020

3.1.1.12

Subfamily: GSX

TAATTA

3.1.1.12.1

GSX-1 (GSH-1)

T05100

3.1.1.12.2

GSX-2 (GSH-2)

T17003

3.1.1.13

Subfamily: MNX

ACTAATTA

3.1.1.13.1

MNX1 (HB9, HLXB9)

T03421

3.1.1.14

Subfamily: MEOX

TAATTA

3.1.1.14.1

MEOX-1 (MOX-1)

T04047

3.1.1.14.2

MEOX-2 (MOX-2)

T04048

3.1.1.15

Subfamily: PDX

TAATTA

3.1.1.15.1

PDX-1 (IPF-1)

T02057

3.1.2

Family: NK-related factors

3.1.2.1

Subfamily: BARHL

AACCAATTA

3.1.2.1.1

BarH-L1

T03920

3.1.2.1.2

BarH-L2

T16779

3.1.2.2

Subfamily: BARX

TAATTA

3.1.2.2.1

BARX-1

T02403

3.1.2.2.2

BARX-2

T11228

3.1.2.3

Subfamily: BSX

TAATTA

3.1.2.3.1

BSX-1 (BSX)

T16798

3.1.2.3.1.1

BSX-1, isoform 1 (Bsxla)

T16797

3.1.2.3.1.2

BSX-1, isoform 2 (Bsxlb)

T16800

3.1.2.4

Subfamily: DBX

TTAATTA

3.1.2.4.1

DBX-1

T08090

3.1.2.4.2

DBX-2

T08092

3.1.2.5

Subfamily: DLX

TAATTA

3.1.2.5.1

DLX-1

T02006

3.1.2.5.2

DLX-2

T02009

3.1.2.5.3

DLX-3

T02409

3.1.2.5.4

DLX-4

T03993

3.1.2.5.5

DLX-5

T03989

3.1.2.5.5.1

DLX-5, isoform 1 (α)

T08471

3.1.2.5.5.2

DLX-5, isoform 2 (β)

T17006

3.1.2.5.5.3

DLX-5, isoform 3 (γ)

T17007

3.1.2.5.6

DLX-6

T03990

F

3.1.2.5.6.1

DLX-6, isoform 1

T14717

3.1.2.5.6.2

DLX-6, isoform 2

T26086

3.1.2.6

Subfamily: EMX

CTAATTAG

3.1.2.6.1

EMX-1

T02011

3.1.2.6.2

EMX-2

T02013

3.1.2.7

Subfamily: EN (Engrailed-like factors)

CTAATTAG

3.1.2.7.1

EN-1

T02016

F

3.1.2.7.2

EN-2

T02020

3.1.2.8

Subfamily: HHEX

ATTAA

3.1.2.8.1

HHEX (PRH)

T03417

3.1.2.9

Subfamily: HLX

TAATTAATTA

3.1.2.9.1

HLX-1 (HB24)

T02053

3.1.2.10

Subfamily: LBX

TTAATTAA

3.1.2.10.1

LBX-1

T04315

3.1.2.10.2

LBX-2

T16903

3.1.2.11

Subfamily: MSX

ACCAATTA

3.1.2.11.1

MSX-1 (HOX7)

T02072

3.1.2.11.2

MSX-2 (HOX8)

T02076

3.1.2.12

Subfamily: NANOG

CCATTT

3.1.2.12.1

NANOG

3.1.2.12.1.1

NANOG, isoform 1

3.1.2.12.1.2

NANOG, isoform 2

3.1.2.13

Subfamily: NK-1

CTAATTAG

3.1.2.13.1

NKX-1.1 (NKX1-1, SAX-2)

T16916

3.1.2.13.2

NKX-1.2 (NKX1-2, SAX-1)

T16801

3.1.2.14

Subfamily: NK-2.1

CCACTTGA

3.1.2.14.1

NKX-2.1 (NKX2-1, TTF-1)

T00859

3.1.2.14.2

NKX-2.4 (NKX2-4, NK-2HD)

T16918

3.1.2.15

Subfamily: NK-2.2

CCACTTGA

3.1.2.15.1

NKX-2.2 (NKX2-2, NKX2B)

T02384

3.1.2.15.2

NKX-2.8 (NKX2-8, NKX2-9, NKX2G, NKX2H)

T04338

3.1.2.16

Subfamily: NK-3

AAGTACTT

3.1.2.16.1

NKX-3.1 (NKX3-1, NKX3A)

T04256

3.1.2.16.2

NKX-3.2 (NKX3-2, NKX3B)

T02667

F

3.1.2.17

Subfamily: NK-4

CCACTTAA

3.1.2.17.1

NKX-2.3 (NKX2-3, NKX2C, NKX4-3)

T04325

3.1.2.17.2

NKX-2.5 (NKX2-5, NKX2E, NKX4-1, CSX)

T01675

3.1.2.17.3

NKX-2.6 (NKX2-6, NKX2F, NKX4-2, CSX2)

T04342

3.1.2.18

Subfamily: NK-5/HMX

AGCAATTAA

3.1.2.18.1

HMX-1 (H6, NKX5-3, NKX-5.3)

T04444

3.1.2.18.2

HMX-2 (H6L, NKX5-2, NKX-5.2)

T22946

3.1.2.18.3

HMX-3 (NKX5-1, NKX-5.1)

T04446

3.1.2.19

Subfamily: NK-6

AATAATTA

3.1.2.19.1

NKX-6.1 (NKX6-1, NKX6A)

T04269

3.1.2.19.2

NKX-6.2 (NKX6-2, NKX6B)

T02050

3.1.2.19.3

NKX-6.3 (NKX6-3)

T16930

3.1.2.20

Subfamily: NOTO

3.1.2.20.1

NOTO

T19770

3.1.2.21

Subfamily: TLX

AATTAATA

3.1.2.21.1

TLX-1 (HOX11, TCL-3)

T02055

3.1.2.21.2

TLX-2 (HOX11L1, NCX)

T04368

3.1.2.21.3

TLX-3 (HOX11L2)

T04314

3.1.2.22

Subfamily: VAX

TAATTA

3.1.2.22.1

VAX-1

T03274

3.1.2.22.1.1

VAX-1, isoform 1

T14527

3.1.2.22.1.2

VAX-1, isoform 2

T26350

3.1.2.22.2

VAX-2

T03276

3.1.2.23

Subfamily: VENTX

3.1.3

Family: Paired-related HD factors

3.1.3.1

Subfamily: ALX

TTAATTAA

3.1.3.1.1

ALX-1 (CART-1)

T03999

3.1.3.1.2

ALX-3

T03343

3.1.3.1.3

ALX-4

T02967

3.1.3.2

Subfamily: ARGFX

3.1.3.3

Subfamily: ARX

TTAATTAA

3.1.3.3.1

ARX

T16770

3.1.3.4

Subfamily: DMBX

GGATTA

3.1.3.4.1

DMBX (MBX, OTX-3, PAXB)

T06253

3.1.3.4.1.1

DMBX, isoform 1

T11177

3.1.3.4.1.2

DMBX, isoform 2

T26087

3.1.3.5

Subfamily: DPRX

3.1.3.6

Subfamily: DRGX

3.1.3.6.1

DRGX (PRRXL1, Drg11)

T19744

3.1.3.6.1.1

DRGX, isoform 1

T25980

3.1.3.6.1.2

DRGX, isoform 2 (Prrxl1-B)

T19743

3.1.3.7

Subfamily: DUX

TCTAATTGAGAATTAC

3.1.3.8

Subfamily: ESX

TTAATTAA

3.1.3.9

Subfamily: GSC

GGATTA

3.1.3.9.1

GSC

T02047

3.1.3.9.2

GSC-2

T04039

3.1.3.10

Subfamily: HESX

TAATTGAATTA

3.1.3.10.1

HESX-1

T02785

3.1.3.11

Subfamily: HOPX

3.1.3.11.1

HOPX-1

T

3.1.3.12

Subfamily: ISX

CTAATTAG

3.1.3.12.1

ISX

T17019

3.1.3.12.1.1

ISX, isoform 1

T17018

3.1.3.12.1.2

ISX, isoform 2

T26163

3.1.3.13

Subfamily: LEUTX

3.1.3.14

Subfamily: MIX

3.1.3.14.1

MIXL1

T04800

3.1.3.15

Subfamily: NOBOX

CTAATTAG

3.1.3.16

Subfamily: OTP

TTAATTAA

3.1.3.16.1

OTP

T16920

3.1.3.17

Subfamily: OTX

GGGATTAA

3.1.3.17.1

OTX-1

T02080

3.1.3.17.2

OTX-2

T02083

3.1.3.17.3

CRX (CORD-2)

T03461

3.1.3.18

Subfamily: PHOX

ATAATTAA

3.1.3.18.1

PHOX-2A (ARIX, PMX2A)

T02090

3.1.3.18.2

PHOX-2B (PMX2B)

T03976

3.1.3.19

Subfamily: PITX

GGGATTAA

3.1.3.19.1

PITX-1 (BFT, PTX1)

T02415

3.1.3.19.2

PITX-2 (ARP, RGS, RIEG1, Ptx2)

T09186

3.1.3.19.2.1

Ptx2A

T02410

3.1.3.19.2.2

Ptx2B

T02412

3.1.3.19.2.3

Ptx2C

T17005

3.1.3.19.2.4

Ptx2Cα

T25959

3.1.3.19.2.5

Ptx2Cβ

T25960

3.1.3.19.3

PITX-3 (PTX3)

T02666

3.1.3.20

Subfamily: PROP

TTAATTAA

3.1.3.20.1

PROP-1

T

3.1.3.21

Subfamily: PRRX

GCTAATTAGC

3.1.3.21.1

PRRX-1 (PHOX1, PMX1)

T02966

3.1.3.21.1.1

PRRX-1, isoform 1 (K2-a)

T02060

3.1.3.21.1.2

PRRX-1, isoform 2 (K2-b)

T02061

3.1.3.21.2

PRRX-2 (PMX2, PRX2)

T01483

3.1.3.22

Subfamily: RAX

CTAATTAG

3.1.3.22.1

RAX (RX)

T03502

3.1.3.23

Subfamily: RHOX

CTAATTAG

3.1.3.24

Subfamily: SEBOX

3.1.3.24.1

SEBOX (OG-9)

T03309

3.1.3.25

Subfamily: SHOX

TTAATTAA

3.1.3.25.2

SHOX-2 (OG-12X, SHOT)

T14734

3.1.3.25.2.1

SHOX-2, isoform 1 (OG12A)

T03310

3.1.3.25.2.2

SHOX-2, isoform 2 (OG12B)

T26289

3.1.3.26

Subfamily: TPRX

3.1.3.27

Subfamily: UNCX

TTAATTAA

3.1.3.27.1

UNCX (Uncx4.1)

T03307

3.1.3.28

Subfamily: VSX

TTAATTAA

3.1.3.28.1

VSX-1 (RINX)

T16785

3.1.3.28.2

VSX-2 (HOX10)

T02970

3.1.4

Family: TALE-type homeo domain factors

3.1.4.1

Subfamily: IRX (Iroquois)

TACATGTA

3.1.4.1.1

IRX-1

T04281

3.1.4.1.2

IRX-2

T14754

3.1.4.1.3

IRX-3

T02439

3.1.4.1.3.1

IRX-3, isoform 1

T11255

3.1.4.1.3.2

IRX-3, isoform 2

T26162

3.1.4.1.4

IRX-4

T04276

3.1.4.1.5

IRX-5

T04283

3.1.4.1.6

IRX-6

T08164

3.1.4.2

Subfamily: MEIS

AGCTGTCAA

3.1.4.2.1

Meis1

T09993

3.1.4.2.1.1

Meis1, isoform 1 (Meis1A)

T03388

3.1.4.2.1.2

Meis1, isoform 2 (Meis1B)

T03389

3.1.4.2.1.3

Meis1, isoform 3

T26190

3.1.4.2.2

Meis2

T11160

3.1.4.2.2.1

Meis2A

T03405

3.1.4.2.2.2

Meis2B

T03407

3.1.4.2.2.3

Meis2C

T03408

3.1.4.2.2.4

Meis2D

T03409

3.1.4.2.3

Meis3

T03406

3.1.4.2.3.1

Meis3, isoform 1

T11188

3.1.4.2.3.2

Meis3, isoform 2

T25908

3.1.4.3

Subfamily: MKX (Mohawk)

3.1.4.3.1

MKX (IRX-L1)

T

3.1.4.4

Subfamily: PBX

CATCAAT

3.1.4.4.1

PBX-1

T08131

3.1.4.4.1.1

PBX-1a

T03451

3.1.4.4.1.2

PBX-1b

T02088

3.1.4.4.2

PBX-2

T04127

3.1.4.4.3

PBX-3

T14296

3.1.4.4.3.1

PBX-3a

T04125

3.1.4.4.3.2

PBX-3b

T04126

3.1.4.4.4

PBX-4

T19780

3.1.4.4.4.1

PBX-4, isoform 1

T19779

3.1.4.4.4.2

PBX-4, isoform 2

T19781

3.1.4.5

Subfamily: PKNOX

ACCTGTCAAT

3.1.4.5.1

PKNOX-1 (PREP-1)

T04121

3.1.4.5.2

PKNOX-2 (PREP-2)

T16934

3.1.4.6

Subfamily: TGIF

AGCTGTCAAT

3.1.4.6.1

TGIF-1

T04077

3.1.4.6.1.1

TGIF-1, isoform 1

T10218

3.1.4.6.1.2

TGIF-1, isoform 2

T17016

3.1.4.6.2

TGIF-2

T16763

3.1.4.6.3

TGIF-2LX

T

3.1.5

Family: HD-LIM factors

AATTAA;

3.1.5.1

Subfamily: ISL

ATCAATTAA

3.1.5.1.1

ISL-1 (Islet-1)

T09161

3.1.5.1.1.1

ISL-1, isoform 1 (α)

T06054

3.1.5.1.1.2

ISL-1, isoform 2 (β)

T06055

3.1.5.1.2

ISL-2 (Islet-2)

T16901

3.1.5.2

Subfamily: Lhx-1-like factors

TTAATTAA

3.1.5.2.1

Lhx1 (Lim-1)

T01961

3.1.5.2.2

Lhx5

T04181

3.1.5.3

Subfamily: Lhx-2-like factors

TAATTA

3.1.5.3.1

Lhx2 (LH-2)

T01969

3.1.5.3.2

Lhx9

T11357

3.1.5.3.2.1

Lhx9, isoform 1 β

T04192

3.1.5.3.2.2

Lhx9, isoform 2 α

T04195

3.1.5.3.2.3

Lhx9, isoform 3

T25470

3.1.5.3.2.4

Lhx9, isoform 4

T26174

3.1.5.4

Subfamily: Lhx-3-like factors

TAATTA

3.1.5.4.1

Lhx3

T10879

3.1.5.4.1.1

Lhx3, isoform A

T01964

3.1.5.4.1.2

Lhx3, isoform B

T04840

3.1.5.4.2

Lhx4

T03542

3.1.5.5

Subfamily: Lhx-6-like factors

CTAATTAG

3.1.5.5.1

Lhx6 (Lhx6.1)

T05162

3.1.5.5.1.1

Lhx6, isoform 1 (Lhx6.1a)

T04187

3.1.5.5.1.2

Lhx6, isoform 2 (Lhx6.1b)

T04188

3.1.5.5.2

Lhx8

T11354

3.1.5.6

Subfamily: Lmx

TTAATTAA

3.1.5.6.1

Lmx-1α (LMX-1.1, LMX1A)

T04300

3.1.5.6.2

Lmx-1β (LMX-1.2, LMX1B)

T04303

3.1.6

Family: HD-SINE factors

GGTATCA

3.1.6.1

Subfamily: SIX1-like factors

GGGTATCA

3.1.6.1.1

SIX1

T03262

3.1.6.1.2

SIX2

T03261

3.1.6.2

Subfamily: SIX3-like factors

GGGTATCA

3.1.6.2.1

SIX3

T09227

3.1.6.2.1.1

SIX3A (α)

T03263

3.1.6.2.1.2

SIX3B (β)

T03270

3.1.6.2.2

SIX6

T03272

3.1.6.3

Subfamily: SIX4-like factors

GGTGTCA

3.1.6.3.1

SIX4

T08392