HNF4A_1

 

 

 

 

A

C

G

T

 

Name

HNF4A

1

266

418

562

109

 

TF group

nuclearreceptor

2

752

39

602

16

 

Polypeptide used

DBD

3

20

2

1355

72

 

Ligand sequence

TGACAG20NGA

4

4

2

18

1355

 

Batch of SELEX experiment

AF

5

213

1355

399

171

 

Seed sequence

NRGTCCAAAGTCCANY

6

40

1355

6

95

 

Hamming distance of sequences to seed

1

7

1355

0

42

6

 

SELEX cycle

4

8

1355

0

14

16

 

Number of repeats

dimeric

9

1355

0

50

0

 

Comment

 

10

0

0

1355

0

 

Representative matrix

yes

11

0

0

2

1355

 

 

 

12

85

1355

172

383

 

 

 

13

3

1355

0

42

 

 

 

14

1355

30

183

236

 

Source:

 

15

449

204

64

637

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

16

53

934

0

421

 

 

 

 

 

 

 

 

 

 

 

 

HNF4A_2

 

 

 

 

A

C

G

T

 

Name

HNF4A

1

508

165

1341

275

 

TF group

nuclearreceptor

2

662

28

1187

17

 

Polypeptide used

DBD

3

12

0

1850

1

 

Ligand sequence

TGACAG20NGA

4

135

29

1850

124

 

Batch of SELEX experiment

AF

5

12

25

619

1850

 

Seed sequence

RRGGTCAAAGTCCRNN

6

0

1850

8

196

 

Hamming distance of sequences to seed

1

7

1850

5

85

0

 

SELEX cycle

4

8

1850

0

46

29

 

Number of repeats

dimeric

9

1850

22

12

8

 

Comment

 

10

0

2

1850

0

 

Representative matrix

no

11

0

0

38

1850

 

 

 

12

69

1850

298

305

 

 

 

13

4

1850

10

132

 

 

 

14

1136

3

713

71

 

Source:

 

15

0

582

429

839

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

16

263

442

327

818

 

 

 

 

 

 

 

 

 

 

 

 

HNF4A_3

 

 

 

 

A

C

G

T

 

Name

HNF4A

1

7141

3937

9609

1599

 

TF group

nuclearreceptor

2

11090

167

11197

211

 

Polypeptide used

full

3

53

36

22287

291

 

Ligand sequence

TCCGTG40NTGC

4

149

24

831

22287

 

Batch of SELEX experiment

AI

5

6116

22287

2315

6075

 

Seed sequence

NRGTCCAAAGTCCANY

6

29

22287

37

505

 

Hamming distance of sequences to seed

1

7

22287

20

437

17

 

SELEX cycle

3

8

22287

8

37

35

 

Number of repeats

dimeric

9

22287

22

260

13

 

Comment

 

10

14

28

22287

21

 

Representative matrix

no

11

35

34

83

22287

 

 

 

12

261

22287

155

2320

 

 

 

13

46

22287

55

321

 

 

 

14

22287

161

3576

276

 

Source:

 

15

8646

5677

2739

5224

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

16

10239

10995

7586

11291

 

 

 

 

 

 

 

 

 

 

 

 

HNF4A_4

 

 

 

 

A

C

G

T

 

Name

HNF4A

1

3446

1525

7715

629

 

TF group

nuclearreceptor

2

3332

52

7829

31

 

Polypeptide used

full

3

7

13

11161

17

 

Ligand sequence

TCCGTG40NTGC

4

420

51

11161

2416

 

Batch of SELEX experiment

AI

5

85

104

1377

11161

 

Seed sequence

RRGGTCAAAGGTCA

6

10

11161

9

90

 

Hamming distance of sequences to seed

1

7

11161

10

54

6

 

SELEX cycle

3

8

11161

19

14

19

 

Number of repeats

dimeric

9

11161

9

55

6

 

Comment

 

10

1

20

11161

8

 

Representative matrix

yes

11

19

27

11161

4326

 

 

 

12

12

95

97

11161

 

Source:

 

13

15

11161

19

121

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

14

11161

44

3016

22

 

 

 

 

 

 

 

 

 

 

 

 

HNF4A_5

 

 

 

 

A

C

G

T

 

Name

HNF4A

1

14045

7433

22343

3351

 

TF group

nuclearreceptor

2

13892

428

22496

216

 

Polypeptide used

full

3

34

38

36388

45

 

Ligand sequence

TCCGTG40NTGC

4

3197

245

36388

9533

 

Batch of SELEX experiment

AI

5

869

1228

8136

36388

 

Seed sequence

RRGGTCAAAGTCCRNN

6

39

36388

55

807

 

Hamming distance of sequences to seed

1

7

36388

26

556

16

 

SELEX cycle

3

8

36388

33

79

67

 

Number of repeats

dimeric

9

36388

42

540

34

 

Comment

 

10

40

43

36388

21

 

Representative matrix

yes

11

37

62

95

36388

 

 

 

12

494

36388

305

4452

 

 

 

13

50

36388

45

525

 

 

 

14

30205

181

6184

517

 

Source:

 

15

12371

9751

4817

9450

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

16

8592

9136

7397

11263

 

 

 

 

 

 

 

 

 

 

 

 

HNF4A_6

 

 

 

 

A

C

G

T

 

Name

HNF4A

1

1033

443

1785

157

 

TF group

nuclearreceptor

2

1251

9

1568

10

 

Polypeptide used

full

3

11

5

2818

22

 

Ligand sequence

TCCGTG40NTGC

4

20

14

52

2818

 

Batch of SELEX experiment

AI

5

670

2818

192

798

 

Seed sequence

RRGTCCAAAGGTCAA

6

13

2818

17

52

 

Hamming distance of sequences to seed

1

7

2818

2

37

0

 

SELEX cycle

3

8

2818

4

10

11

 

Number of repeats

dimeric

9

2818

5

21

9

 

Comment

 

10

1

7

2818

12

 

Representative matrix

no

11

14

12

2818

1327

 

 

 

12

10

60

50

2818

 

 

 

13

5

2818

8

48

 

Source:

 

14

2818

9

635

6

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

15

2818

2302

919

2089

 

 

 

 

 

 

 

 

 

 

 

 

Hnf4a_7

 

 

 

 

A

C

G

T

 

Name

Hnf4a

1

1870

587

3292

467

 

TF group

nuclearreceptor

2

1624

23

3538

5

 

Polypeptide used

DBD

3

6

0

5162

1

 

Ligand sequence

TCCACG20NCG

4

211

14

5162

711

 

Batch of SELEX experiment

Z

5

148

66

564

5162

 

Seed sequence

RRGGTCAAAGTCCRNN

6

1

5162

5

122

 

Hamming distance of sequences to seed

1

7

5162

2

159

0

 

SELEX cycle

4

8

5162

0

69

11

 

Number of repeats

dimeric

9

5162

0

52

0

 

Comment

 

10

0

1

5162

3

 

Representative matrix

no

11

0

5

7

5162

 

 

 

12

129

5162

131

962

 

 

 

13

0

5162

4

191

 

 

 

14

4452

35

709

135

 

Source:

 

15

2148

1109

1121

784

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

16

1019

1064

906

2174