EN1_m1

 

 

 

 

A

C

G

T

 

Name

EN1

1

908

1000

981

402

 

TF group

homeodomain

2

393

1544

773

581

 

Polypeptide used

DBD

3

116

1803

65

1488

 

Ligand sequence

TGTAGG20NGA

4

3291

263

186

124

 

Batch of SELEX experiment

Y

5

3291

57

0

70

 

Seed sequence

NNYAATTANN

6

0

51

27

3291

 

Hamming distance of sequences to seed

1

7

92

448

257

3291

 

SELEX cycle

3

8

3291

42

49

271

 

Number of repeats

monomeric

9

933

670

1211

477

 

Comment

 

10

494

1266

778

753

 

Representative matrix

no

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Source:

 

 

 

 

 

 

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

 

 

 

 

 

 

 

 

 

EN1_d1

 

 

 

 

A

C

G

T

 

Name

EN1

1

58

27

19

1258

 

TF group

homeodomain

2

1060

15

113

44

 

Polypeptide used

DBD

3

1101

6

8

12

 

Ligand sequence

TGTAGG20NGA

4

30

16

46

1276

 

Batch of SELEX experiment

Y

5

75

38

147

1158

 

Seed sequence

TAATTRSNYAATTA

6

517

9

791

23

 

Hamming distance of sequences to seed

2

7

50

450

745

33

 

SELEX cycle

3

8

138

365

184

394

 

Number of repeats

dimeric

9

24

672

26

429

 

Comment

 

10

993

103

76

80

 

Representative matrix

yes

11

1112

45

13

56

 

 

 

12

11

14

13

1263

 

Source:

 

13

108

91

11

1203

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

14

1072

28

49

98

 

 

 

 

 

 

 

 

 

 

 

 

EN1_m2

 

 

 

 

A

C

G

T

 

Name

EN1

1

427

1174

765

525

 

TF group

homeodomain

2

104

1328

5

1562

 

Polypeptide used

full

3

2891

99

71

0

 

Ligand sequence

TGACCT20NCCA

4

2891

28

0

0

 

Batch of SELEX experiment

W

5

0

0

0

2891

 

Seed sequence

NYAATTAN

6

57

483

162

2891

 

Hamming distance of sequences to seed

1

7

2891

0

30

132

 

SELEX cycle

3

8

689

683

1216

302

 

Number of repeats

monomeric

 

 

 

 

 

 

Comment

 

 

 

 

 

 

 

Representative matrix

no

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Source:

 

 

 

 

 

 

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

 

 

 

 

 

 

 

 

 

EN1_d2

 

 

 

 

A

C

G

T

 

Name

EN1

1

35

46

34

434

 

TF group

homeodomain

2

317

23

113

95

 

Polypeptide used

full

3

345

16

54

45

 

Ligand sequence

TGACCT20NCCA

4

51

60

107

428

 

Batch of SELEX experiment

W

5

55

57

132

411

 

Seed sequence

TAATTRSNYAATTA

6

192

21

233

20

 

Hamming distance of sequences to seed

2

7

37

263

257

2

 

SELEX cycle

4

8

79

114

117

137

 

Number of repeats

dimeric

9

19

230

23

243

 

Comment

 

10

348

111

75

40

 

Representative matrix

no

11

364

72

62

62

 

 

 

12

41

61

40

421

 

Source:

 

13

72

51

67

395

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

14

348

21

80

56