OTX1_d1

 

 

 

 

A

C

G

T

 

Name

OTX1

1

245

418

517

343

 

TF group

homeodomain

2

418

366

268

471

 

Polypeptide used

DBD

3

68

58

8

1522

 

Ligand sequence

TGATAA20NGA

4

1522

7

34

26

 

Batch of SELEX experiment

Y

5

1522

1

4

0

 

Seed sequence

NNTAATCCGATTANN

6

64

43

347

1522

 

Hamming distance of sequences to seed

1

7

28

1522

112

0

 

SELEX cycle

3

8

30

1522

0

33

 

Number of repeats

dimeric

9

7

12

1522

237

 

Comment

 

10

1522

731

42

61

 

Representative matrix

no

11

6

22

2

1522

 

 

 

12

87

71

8

1522

 

 

 

13

1522

23

60

130

 

Source:

 

14

534

327

257

404

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

15

396

523

322

280

 

 

 

 

 

 

 

 

 

 

 

 

OTX1_m1

 

 

 

 

A

C

G

T

 

Name

OTX1

1

5118

6501

3186

8636

 

TF group

homeodomain

2

745

90

0

23441

 

Polypeptide used

DBD

3

23441

0

254

544

 

Ligand sequence

TGATAA20NGA

4

23441

0

0

0

 

Batch of SELEX experiment

Y

5

243

0

3160

23441

 

Seed sequence

NTAATCCN

6

647

23441

659

378

 

Hamming distance of sequences to seed

1

7

789

23441

8662

3363

 

SELEX cycle

3

8

1873

6182

10599

4787

 

Number of repeats

monomeric

 

 

 

 

 

 

Comment

 

 

 

 

 

 

 

Representative matrix

yes

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Source:

 

 

 

 

 

 

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

 

 

 

 

 

 

 

 

 

Otx1_d2

 

 

 

 

A

C

G

T

 

Name

Otx1

1

123

129

168

160

 

TF group

homeodomain

2

153

142

77

208

 

Polypeptide used

DBD

3

40

16

0

580

 

Ligand sequence

TCTTAG20NATG

4

580

0

20

17

 

Batch of SELEX experiment

AC

5

580

0

1

0

 

Seed sequence

NNTAATCCGATTANN

6

10

5

117

580

 

Hamming distance of sequences to seed

1

7

6

580

50

0

 

SELEX cycle

3

8

20

580

0

14

 

Number of repeats

dimeric

9

4

11

580

69

 

Comment

 

10

580

195

12

34

 

Representative matrix

yes

11

6

6

1

580

 

 

 

12

30

8

0

580

 

 

 

13

580

7

21

51

 

Source:

 

14

194

90

149

147

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

15

142

192

137

109

 

 

 

 

 

 

 

 

 

 

 

 

Otx1_m2

 

 

 

 

A

C

G

T

 

Name

Otx1

1

1260

1057

584

1626

 

TF group

homeodomain

2

213

201

0

4527

 

Polypeptide used

DBD

3

4527

259

344

195

 

Ligand sequence

TCTTAG20NATG

4

4527

5

35

0

 

Batch of SELEX experiment

AC

5

0

154

595

4527

 

Seed sequence

NTAATCCN

6

292

4527

212

121

 

Hamming distance of sequences to seed

1

7

158

4527

493

1193

 

SELEX cycle

3

8

614

1015

1604

1294

 

Number of repeats

monomeric

 

 

 

 

 

 

Comment

 

 

 

 

 

 

 

Representative matrix

no

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Source:

 

 

 

 

 

 

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764