ISX_1

 

 

 

 

A

C

G

T

 

Name

ISX

1

687

1148

735

1752

 

TF group

homeodomain

2

131

65

61

4323

 

Polypeptide used

DBD

3

4323

38

136

296

 

Ligand sequence

TATTTA20NCG

4

4323

121

170

32

 

Batch of SELEX experiment

Y

5

351

557

376

4323

 

Seed sequence

NTAATYTAATTAN

6

28

2948

275

1375

 

Hamming distance of sequences to seed

1

7

22

684

317

4323

 

SELEX cycle

3

8

4323

19

23

10

 

Number of repeats

dimeric

9

4323

16

7

2

 

Comment

 

10

0

16

2

4323

 

Representative matrix

yes

11

10

4

11

4323

 

 

 

12

4323

6

77

86

 

Source:

 

13

1653

739

1269

662

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

 

 

 

 

 

 

 

 

 

ISX_2

 

 

 

 

A

C

G

T

 

Name

ISX

1

2059

9764

2902

4429

 

TF group

homeodomain

2

878

11027

283

8127

 

Polypeptide used

DBD

3

19154

867

286

571

 

Ligand sequence

TATTTA20NCG

4

19154

175

0

72

 

Batch of SELEX experiment

Y

5

0

0

0

19154

 

Seed sequence

NYAATTAN

6

380

458

248

19154

 

Hamming distance of sequences to seed

1

7

19154

143

68

744

 

SELEX cycle

2

8

7187

3922

5442

2603

 

Number of repeats

monomeric

 

 

 

 

 

 

Comment

 

 

 

 

 

 

 

Representative matrix

no

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Source:

 

 

 

 

 

 

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

 

 

 

 

 

 

 

 

 

ISX_3

 

 

 

 

A

C

G

T

 

Name

ISX

1

318

863

364

520

 

TF group

homeodomain

2

10

1003

0

1061

 

Polypeptide used

full

3

2065

48

5

24

 

Ligand sequence

TGAGTG20NTGA

4

2065

16

0

10

 

Batch of SELEX experiment

AE

5

0

0

0

2065

 

Seed sequence

NYAATTAN

6

0

0

24

2065

 

Hamming distance of sequences to seed

1

7

2065

0

0

49

 

SELEX cycle

2

8

770

307

704

283

 

Number of repeats

monomeric

 

 

 

 

 

 

Comment

 

 

 

 

 

 

 

Representative matrix

no

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Source:

 

 

 

 

 

 

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764