SPDEF_1

 

 

 

 

A

C

G

T

 

Name

SPDEF

1

498

10

10

92

 

TF group

ETS

2

214

284

37

13

 

Polypeptide used

DBD

3

2

498

22

0

 

Ligand sequence

TCGCTG20NTCT

4

21

498

0

0

 

Batch of SELEX experiment

AD

5

0

5

498

0

 

Seed sequence

AMCCGGATGTN

6

10

0

498

0

 

Hamming distance of sequences to seed

1

7

498

0

1

1

 

SELEX cycle

4

8

77

21

7

498

 

Number of repeats

monomeric

9

158

40

498

39

 

Comment

 

10

0

81

0

498

 

Representative matrix

yes

11

236

25

89

148

 

Source:

 

 

 

 

 

 

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

 

 

 

 

 

 

 

 

 

SPDEF_2

 

 

 

 

A

C

G

T

 

Name

SPDEF

1

79

16

238

46

 

TF group

ETS

2

48

13

51

196

 

Polypeptide used

DBD

3

31

14

224

89

 

Ligand sequence

TCGCTG20NTCT

4

7

32

227

77

 

Batch of SELEX experiment

AD

5

31

0

4

205

 

Seed sequence

GTGGTCCCGGATYAT

6

0

285

12

0

 

Hamming distance of sequences to seed

2

7

0

271

4

3

 

SELEX cycle

4

8

0

272

0

0

 

Number of repeats

putative multimer

9

0

0

235

0

 

Comment

 

10

0

0

232

3

 

Representative matrix

yes

11

232

4

0

2

 

 

 

12

15

10

0

201

 

 

 

13

3

71

0

162

 

Source:

 

14

239

1

0

7

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

15

20

33

22

175

 

 

 

 

 

 

 

 

 

 

 

 

SPDEF_3

 

 

 

 

A

C

G

T

 

Name

SPDEF

1

1468

675

2903

720

 

TF group

ETS

2

312

5037

385

277

 

Polypeptide used

DBD

3

5473

203

170

103

 

Ligand sequence

TCGCTG20NTCT

4

97

1

5689

33

 

Batch of SELEX experiment

AD

5

2053

243

1386

2085

 

Seed sequence

NCAGNAAGAMGTAWMM

6

5750

3

4

26

 

Hamming distance of sequences to seed

3

7

5764

22

58

0

 

SELEX cycle

4

8

1179

21

4700

33

 

Number of repeats

putative multimer

9

5403

4

443

7

 

Comment

 

10

4410

1265

0

116

 

Representative matrix

yes

11

68

139

5764

0

 

 

 

12

124

76

249

5683

 

 

 

13

5731

0

99

273

 

 

 

14

2366

3

0

3405

 

Source:

 

15

3784

850

7

1299

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

16

1829

3732

30

341

 

 

 

 

 

 

 

 

 

 

 

 

SPDEF_4

 

 

 

 

A

C

G

T

 

Name

SPDEF

1

4628

101

176

912

 

TF group

ETS

2

1890

2737

536

77

 

Polypeptide used

full

3

52

4628

92

0

 

Ligand sequence

TCATTG20NCG

4

237

4628

1

1

 

Batch of SELEX experiment

AD

5

2

2

4628

0

 

Seed sequence

AMCCGGATGTN

6

6

0

4628

8

 

Hamming distance of sequences to seed

1

7

4628

0

6

2

 

SELEX cycle

3

8

532

69

11

4628

 

Number of repeats

monomeric

9

1566

601

4628

66

 

Comment

 

10

58

1345

28

4628

 

Representative matrix

no

11

1911

568

1339

810

 

Source:

 

 

 

 

 

 

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

 

 

 

 

 

 

 

 

 

SPDEF_5

 

 

 

 

A

C

G

T

 

Name

SPDEF

1

112

55

664

154

 

TF group

ETS

2

148

21

350

747

 

Polypeptide used

full

3

73

19

673

180

 

Ligand sequence

TCATTG20NCG

4

16

11

702

12

 

Batch of SELEX experiment

AD

5

28

28

11

945

 

Seed sequence

GTGGTCCCGGATYAT

6

15

1583

19

5

 

Hamming distance of sequences to seed

2

7

1

1604

8

1

 

SELEX cycle

3

8

0

1602

0

0

 

Number of repeats

putative multimer

9

0

0

703

0

 

Comment

 

10

0

0

703

1

 

Representative matrix

no

11

1271

8

0

5

 

 

 

12

16

16

4

937

 

 

 

13

11

648

1

553

 

Source:

 

14

1216

50

4

186

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

15

183

164

125

770

 

 

 

 

 

 

 

 

 

 

 

 

SPDEF_6

 

 

 

 

A

C

G

T

 

Name

SPDEF

1

493

334

1423

83

 

TF group

ETS

2

129

2103

183

62

 

Polypeptide used

full

3

2189

183

86

40

 

Ligand sequence

TCATTG20NCG

4

69

36

2278

44

 

Batch of SELEX experiment

AD

5

828

241

532

731

 

Seed sequence

NCAGNAAGAMGTAWMM

6

2329

8

0

2

 

Hamming distance of sequences to seed

3

7

2329

14

33

0

 

SELEX cycle

3

8

587

37

1838

12

 

Number of repeats

putative multimer

9

2001

9

333

29

 

Comment

 

10

1259

1016

15

60

 

Representative matrix

no

11

0

84

2334

0

 

 

 

12

5

0

224

2232

 

 

 

13

2331

0

17

102

 

 

 

14

1605

0

0

723

 

Source:

 

15

888

1103

4

409

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

16

1430

875

15

53